TY - CHAP
T1 - A Timeline of Perezone, the First Isolated Secondary Metabolite in the New World, Covering the Period from 1852 to 2020
AU - Escobedo-González, René
AU - Mendoza, Pablo
AU - Nicolás-Vázquez, María Inés
AU - Hernández-Rodríguez, Maricarmen
AU - Martínez, Joel
AU - Miranda Ruvalcaba, René
N1 - Publisher Copyright:
© 2021, The Author(s), under exclusive license to Springer Nature Switzerland AG.
PY - 2021
Y1 - 2021
N2 - This chapter covers a sesquiterpene quinone, commonly named perezone. This molecule is documented as the first secondary metabolite isolated in crystalline form in the New World in 1852. An introduction, with its structure, the IUPAC nomenclature, and the most recent physical and spectroscopic characterizations are firstly described initially. Alongside this, a timeline and scheme with summarized information of the history of this molecule is given including the “Códice Badiano de la Cruz, 1552, highlighting the year of its isolation culminating with information up to 2005. Subsequently, in a chronological order the most recent advances of the target molecule are included and organized in subsections covering the last 15-year period 2006–2020. Finally, recently submitted contributions from the laboratory of the authors are described. It is important to note that the details provided highlight the importance and relevance of perezone.
AB - This chapter covers a sesquiterpene quinone, commonly named perezone. This molecule is documented as the first secondary metabolite isolated in crystalline form in the New World in 1852. An introduction, with its structure, the IUPAC nomenclature, and the most recent physical and spectroscopic characterizations are firstly described initially. Alongside this, a timeline and scheme with summarized information of the history of this molecule is given including the “Códice Badiano de la Cruz, 1552, highlighting the year of its isolation culminating with information up to 2005. Subsequently, in a chronological order the most recent advances of the target molecule are included and organized in subsections covering the last 15-year period 2006–2020. Finally, recently submitted contributions from the laboratory of the authors are described. It is important to note that the details provided highlight the importance and relevance of perezone.
KW - Chemical modifications
KW - Isolation
KW - Perezone
KW - Pharmacological evaluations
KW - Sesquiterpene quinone
KW - Theoretic studies
UR - http://www.scopus.com/inward/record.url?scp=85121014743&partnerID=8YFLogxK
U2 - 10.1007/978-3-030-80560-9_3
DO - 10.1007/978-3-030-80560-9_3
M3 - Capítulo
C2 - 34698946
AN - SCOPUS:85121014743
T3 - Progress in the Chemistry of Organic Natural Products
SP - 67
EP - 133
BT - Progress in the Chemistry of Organic Natural Products
PB - Springer Science and Business Media Deutschland GmbH
ER -