A green approach to the production of 2-pyridone derivatives promoted by infrared irradiation

Fernando Hernández, Fabiola De la Cruz, Julio López, Eduardo Peña, Francisco Delgado, Yolanda Alcaraz, Juvencio Robles, Minerva Martínez-Alfaro, Miguel A. Vázquez

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

An alternative is presented for promoting a reaction with infrared irradiation to obtain different 4-aryl-3-cyano-5-ethoxycarbonyl-6-methyl-2-pyridone derivatives 9a-k. The process was carried out with a green approach from the corresponding 4H-pyrans, using mild reaction conditions and infrared irradiation as the energy source. In the first stage, the reaction produced 1,2,3,4-tetrahydropyridin-2-one derivatives 8a-k, followed by an oxidative step to afford the target molecules in good yields. The structure of products 9a-k was confirmed by FT-IR, 1H NMR and 13C NMR spectroscopic techniques and X-ray diffraction. It was found that the efficiency of the reaction depends on the catalyst and the solvent, as well as on the aldehyde substituents. © 2014, Sociedad Química de México.
Original languageAmerican English
Pages (from-to)152-158
Number of pages136
JournalJournal of the Mexican Chemical Society
StatePublished - 1 Jan 2014
Externally publishedYes

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Nuclear magnetic resonance
Irradiation
Infrared radiation
Derivatives
Pyrans
Aldehydes
X ray diffraction
Catalysts
Molecules
2-hydroxypyridine

Cite this

Hernández, F., De la Cruz, F., López, J., Peña, E., Delgado, F., Alcaraz, Y., ... Vázquez, M. A. (2014). A green approach to the production of 2-pyridone derivatives promoted by infrared irradiation. Journal of the Mexican Chemical Society, 152-158.
Hernández, Fernando ; De la Cruz, Fabiola ; López, Julio ; Peña, Eduardo ; Delgado, Francisco ; Alcaraz, Yolanda ; Robles, Juvencio ; Martínez-Alfaro, Minerva ; Vázquez, Miguel A. / A green approach to the production of 2-pyridone derivatives promoted by infrared irradiation. In: Journal of the Mexican Chemical Society. 2014 ; pp. 152-158.
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Hernández, F, De la Cruz, F, López, J, Peña, E, Delgado, F, Alcaraz, Y, Robles, J, Martínez-Alfaro, M & Vázquez, MA 2014, 'A green approach to the production of 2-pyridone derivatives promoted by infrared irradiation', Journal of the Mexican Chemical Society, pp. 152-158.

A green approach to the production of 2-pyridone derivatives promoted by infrared irradiation. / Hernández, Fernando; De la Cruz, Fabiola; López, Julio; Peña, Eduardo; Delgado, Francisco; Alcaraz, Yolanda; Robles, Juvencio; Martínez-Alfaro, Minerva; Vázquez, Miguel A.

In: Journal of the Mexican Chemical Society, 01.01.2014, p. 152-158.

Research output: Contribution to journalArticle

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AU - Hernández, Fernando

AU - De la Cruz, Fabiola

AU - López, Julio

AU - Peña, Eduardo

AU - Delgado, Francisco

AU - Alcaraz, Yolanda

AU - Robles, Juvencio

AU - Martínez-Alfaro, Minerva

AU - Vázquez, Miguel A.

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