Project Details
Description
1. To evaluate the possible toxic effect of repeated administration for 28 days of methanolic extracts from wild Buddleja cordata Kunth and its cell suspension cultures
2. To evaluate the anti-arthritic activity of methanolic extracts in a murine model of experimental arthritis in mouse
3. To determine oxidative stress biomarkers in tissue obtained from arthritic mice
2. To evaluate the anti-arthritic activity of methanolic extracts in a murine model of experimental arthritis in mouse
3. To determine oxidative stress biomarkers in tissue obtained from arthritic mice
Key findings
La línea celular de Buddleja cordata no generó ningun tipo de toxicidad o letalidad, al igual que los extractos de la planta silvestre, los cuáles fueron administrados vía intragástrica en ratones sanos por 28 días, y en cuanto al modelo de artritis la línea celular mostró un mayor efecto antiedematoso que el extracto de la planta silvestre.
| Short title | Buddleja cordata |
|---|---|
| Acronym | Vegetal biotechnology |
| Status | Finished |
| Effective start/end date | 31/08/17 → 28/09/18 |
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