TY - JOUR
T1 - Vibrational circular dichroism
T2 - Recent advances for the assignment of the absolute configuration of natural products
AU - Burgueño-Tapia, Eleuterio
AU - Joseph-Nathan, Pedro
PY - 2015/10
Y1 - 2015/10
N2 - Vibrational circular dichroism (VCD) emerged during the last decade as a reliable tool for the absolute configuration (AC) determination of organic compounds. The principles, instrumentation, and methodology applied prior to early 2013 were recently reviewed by us. Since VCD is a very dynamic field, the aim of this review is to update VCD advances for the AC assignment of terpenoids, aromatic compounds, alkaloids, and other natural products for the 2013-2014 period, when VCD was applied to the AC assignment of some 70 natural products. In addition, although discovered in 2012, a brief introduction to the VCD exciton coupling approach and its applications in natural products AC assignment is presented.
AB - Vibrational circular dichroism (VCD) emerged during the last decade as a reliable tool for the absolute configuration (AC) determination of organic compounds. The principles, instrumentation, and methodology applied prior to early 2013 were recently reviewed by us. Since VCD is a very dynamic field, the aim of this review is to update VCD advances for the AC assignment of terpenoids, aromatic compounds, alkaloids, and other natural products for the 2013-2014 period, when VCD was applied to the AC assignment of some 70 natural products. In addition, although discovered in 2012, a brief introduction to the VCD exciton coupling approach and its applications in natural products AC assignment is presented.
KW - Absolute configuration
KW - Natural products
KW - Vibrational circular dichroism
KW - Vibrational circular dichroism exciton coupling
UR - http://www.scopus.com/inward/record.url?scp=84954240108&partnerID=8YFLogxK
U2 - 10.1177/1934578x1501001036
DO - 10.1177/1934578x1501001036
M3 - Artículo de revisión
C2 - 26669125
AN - SCOPUS:84954240108
SN - 1934-578X
VL - 10
SP - 1785
EP - 1795
JO - Natural Product Communications
JF - Natural Product Communications
IS - 10
ER -