Synthesis and characterization of two danazol derivatives

Lauro Figueroa-Valverde, Francisco Díaz-Cedillo, Maria López-Ramos, Elodia Garcia-Cervera

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2 Citas (Scopus)

Resumen

Two danazol derivatives were synthesized and characterized by spectral analyses. In order to characterize the structural and chemical requirements of danazol derivatives, several parameters such as logP, π, Rm and Vm were evaluated. The results showed an increase in the values of logP for the compound 6 in comparison with 3. The compound 3 showed an increase in the values of π, Rm and Vm with respect to 6. These data indicate a high degree of lipophilicity and a low steric impediment for compound 6 in comparison with 3.

Idioma originalInglés
Páginas (desde-hasta)S191-S196
PublicaciónE-Journal of Chemistry
Volumen7
N.ºSUPPL. 1
DOI
EstadoPublicada - dic. 2010
Publicado de forma externa

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