Prolonged Computer Use by Office Workers Induces Ocular Symptoms Associated With Tear Film Alterations and Overexpression of Mucin 5 AC and Catalase

Alejandra Saavedra Morales; Cesar Antonio Gonzalez Diaz; Guadalupe Cleva Villanueva López; Omar Padilla Juárez; Ana Laura Luna Torres; Virginia Sanchez Monroy

doi:10.1097/JOM.0000000000002653

Prolonged Computer Use by Office Workers Induces Ocular Symptoms Associated With Tear Film Alterations and Overexpression of Mucin 5 AC and Catalase

Título traducido de la contribución: El uso prolongado de computadora en trabajadores de oficinas produce síntomas oftalmológicos asociados a alteración de la lágrima y sovre exopresión de mucina 5 AC y catalasa

Alejandra Saavedra Morales, Cesar Antonio Gonzalez Diaz, Guadalupe Cleva Villanueva López, Omar Padilla Juárez, Ana Laura Luna Torres, Virginia Sanchez Monroy

Escuela Superior de Medicina (ESM)

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Resumen

The aimof the study was to evaluate officeworkers for symptoms of
computer vision syndrome (CVS) and alterations in the tear film relate to the
hours of daily computer use. Methods: Sixty-seven volunteers were divided
into 2 groups: 2 to 6 and 7 to 12 hours of daily computer use. Computer vision
syndrome symptoms, tear film stability by tear film break-up time test, and
composition of mucin 5 AC, catalase, and IL-6 was assessed by relative gene
expression of conjunctival impression cytology samples were examined. Results:
All participants exhibited moderate symptoms of CVS, whereas 90%
showed reduced tear film stability. For the 7- to 12-hour (vs 2- to 6-hour) group,
these effectswere more pronounced and overexpression of mucin 5 AC and catalase
was detected. Conclusions: Prolonged computer use induced an overexpression
of mucin 5 AC and catalase and instability of the tear film, associated
with ocular symptoms

Título traducido de la contribución	El uso prolongado de computadora en trabajadores de oficinas produce síntomas oftalmológicos asociados a alteración de la lágrima y sovre exopresión de mucina 5 AC y catalasa
Idioma original	Inglés
Número de artículo	1
Páginas (desde-hasta)	34-38
Número de páginas	5
Publicación	International Journal of Occupational and Environmental Health
Volumen	65
N.º	1
DOI	https://doi.org/10.1097/JOM.0000000000002653
Estado	Publicada - 1 ene. 2023

Palabras clave

catalase
computer vision syndrome
IL-6
mucin 5A
tear film

Acceder al documento

10.1097/JOM.0000000000002653

Citar esto

Saavedra Morales, A., Gonzalez Diaz, C. A., Villanueva López, G. C., Padilla Juárez, O., Luna Torres, A. L., & Monroy, V. S. (2023). Prolonged Computer Use by Office Workers Induces Ocular Symptoms Associated With Tear Film Alterations and Overexpression of Mucin 5 AC and Catalase. International Journal of Occupational and Environmental Health, 65(1), 34-38. Artículo 1. https://doi.org/10.1097/JOM.0000000000002653

@article{b629769e99a24377951d22bb623971c4,

title = "Prolonged Computer Use by Office Workers Induces Ocular Symptoms Associated With Tear Film Alterations and Overexpression of Mucin 5 AC and Catalase",

abstract = "The aimof the study was to evaluate officeworkers for symptoms ofcomputer vision syndrome (CVS) and alterations in the tear film relate to thehours of daily computer use. Methods: Sixty-seven volunteers were dividedinto 2 groups: 2 to 6 and 7 to 12 hours of daily computer use. Computer visionsyndrome symptoms, tear film stability by tear film break-up time test, andcomposition of mucin 5 AC, catalase, and IL-6 was assessed by relative geneexpression of conjunctival impression cytology samples were examined. Results:All participants exhibited moderate symptoms of CVS, whereas 90%showed reduced tear film stability. For the 7- to 12-hour (vs 2- to 6-hour) group,these effectswere more pronounced and overexpression of mucin 5 AC and catalasewas detected. Conclusions: Prolonged computer use induced an overexpressionof mucin 5 AC and catalase and instability of the tear film, associatedwith ocular symptoms",

keywords = "catalase, computer vision syndrome, IL-6, mucin 5A, tear film",

author = "{Saavedra Morales}, Alejandra and {Gonzalez Diaz}, {Cesar Antonio} and {Villanueva L{\'o}pez}, {Guadalupe Cleva} and {Padilla Ju{\'a}rez}, Omar and {Luna Torres}, {Ana Laura} and Monroy, {Virginia Sanchez}",

year = "2023",

month = jan,

day = "1",

doi = "10.1097/JOM.0000000000002653",

language = "Ingl{\'e}s",

volume = "65",

pages = "34--38",

journal = "International Journal of Occupational and Environmental Health",

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Saavedra Morales, A, Gonzalez Diaz, CA , Villanueva López, GC, Padilla Juárez, O, Luna Torres, AL & Monroy, VS 2023, 'Prolonged Computer Use by Office Workers Induces Ocular Symptoms Associated With Tear Film Alterations and Overexpression of Mucin 5 AC and Catalase', International Journal of Occupational and Environmental Health, vol. 65, n.º 1, 1, pp. 34-38. https://doi.org/10.1097/JOM.0000000000002653

Prolonged Computer Use by Office Workers Induces Ocular Symptoms Associated With Tear Film Alterations and Overexpression of Mucin 5 AC and Catalase. / Saavedra Morales, Alejandra; Gonzalez Diaz, Cesar Antonio ; Villanueva López, Guadalupe Cleva et al.
En: International Journal of Occupational and Environmental Health, Vol. 65, N.º 1, 1, 01.01.2023, p. 34-38.

Producción científica: Contribución a una revista › Artículo › revisión exhaustiva

TY - JOUR

T1 - Prolonged Computer Use by Office Workers Induces Ocular Symptoms Associated With Tear Film Alterations and Overexpression of Mucin 5 AC and Catalase

AU - Saavedra Morales, Alejandra

AU - Gonzalez Diaz, Cesar Antonio

AU - Villanueva López, Guadalupe Cleva

AU - Padilla Juárez, Omar

AU - Luna Torres, Ana Laura

AU - Monroy, Virginia Sanchez

PY - 2023/1/1

Y1 - 2023/1/1

N2 - The aimof the study was to evaluate officeworkers for symptoms ofcomputer vision syndrome (CVS) and alterations in the tear film relate to thehours of daily computer use. Methods: Sixty-seven volunteers were dividedinto 2 groups: 2 to 6 and 7 to 12 hours of daily computer use. Computer visionsyndrome symptoms, tear film stability by tear film break-up time test, andcomposition of mucin 5 AC, catalase, and IL-6 was assessed by relative geneexpression of conjunctival impression cytology samples were examined. Results:All participants exhibited moderate symptoms of CVS, whereas 90%showed reduced tear film stability. For the 7- to 12-hour (vs 2- to 6-hour) group,these effectswere more pronounced and overexpression of mucin 5 AC and catalasewas detected. Conclusions: Prolonged computer use induced an overexpressionof mucin 5 AC and catalase and instability of the tear film, associatedwith ocular symptoms

AB - The aimof the study was to evaluate officeworkers for symptoms ofcomputer vision syndrome (CVS) and alterations in the tear film relate to thehours of daily computer use. Methods: Sixty-seven volunteers were dividedinto 2 groups: 2 to 6 and 7 to 12 hours of daily computer use. Computer visionsyndrome symptoms, tear film stability by tear film break-up time test, andcomposition of mucin 5 AC, catalase, and IL-6 was assessed by relative geneexpression of conjunctival impression cytology samples were examined. Results:All participants exhibited moderate symptoms of CVS, whereas 90%showed reduced tear film stability. For the 7- to 12-hour (vs 2- to 6-hour) group,these effectswere more pronounced and overexpression of mucin 5 AC and catalasewas detected. Conclusions: Prolonged computer use induced an overexpressionof mucin 5 AC and catalase and instability of the tear film, associatedwith ocular symptoms

KW - catalase

KW - computer vision syndrome

KW - IL-6

KW - mucin 5A

KW - tear film

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DO - 10.1097/JOM.0000000000002653

M3 - Artículo

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SN - 1077-3525

VL - 65

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JO - International Journal of Occupational and Environmental Health

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Saavedra Morales A, Gonzalez Diaz CA , Villanueva López GC, Padilla Juárez O, Luna Torres AL, Monroy VS. Prolonged Computer Use by Office Workers Induces Ocular Symptoms Associated With Tear Film Alterations and Overexpression of Mucin 5 AC and Catalase. International Journal of Occupational and Environmental Health. 2023 ene. 1;65(1):34-38. 1. doi: 10.1097/JOM.0000000000002653