TY - JOUR
T1 - Platelet-rich plasma peptides
T2 - Key for regeneration
AU - Sánchez-González, Dolores Javier
AU - Méndez-Bolaina, Enrique
AU - Trejo-Bahena, Nayeli Isabel
PY - 2012
Y1 - 2012
N2 - Platelet-derived Growth Factors (GFs) are biologically active peptides that enhance tissue repair mechanisms such as angiogenesis, extracellular matrix remodeling, and cellular effects as stem cells recruitment, chemotaxis, cell proliferation, and differentiation. Platelet-rich plasma (PRP) is used in a variety of clinical applications, based on the premise that higher GF content should promote better healing. Platelet derivatives represent a promising therapeutic modality, offering opportunities for treatment of wounds, ulcers, soft-tissue injuries, and various other applications in cell therapy. PRP can be combined with cell-based therapies such as adipose-derived stem cells, regenerative cell therapy, and transfer factors therapy. This paper describes the biological background of the platelet-derived substances and their potential use in regenerative medicine.
AB - Platelet-derived Growth Factors (GFs) are biologically active peptides that enhance tissue repair mechanisms such as angiogenesis, extracellular matrix remodeling, and cellular effects as stem cells recruitment, chemotaxis, cell proliferation, and differentiation. Platelet-rich plasma (PRP) is used in a variety of clinical applications, based on the premise that higher GF content should promote better healing. Platelet derivatives represent a promising therapeutic modality, offering opportunities for treatment of wounds, ulcers, soft-tissue injuries, and various other applications in cell therapy. PRP can be combined with cell-based therapies such as adipose-derived stem cells, regenerative cell therapy, and transfer factors therapy. This paper describes the biological background of the platelet-derived substances and their potential use in regenerative medicine.
UR - http://www.scopus.com/inward/record.url?scp=84879193656&partnerID=8YFLogxK
U2 - 10.1155/2012/532519
DO - 10.1155/2012/532519
M3 - Artículo de revisión
C2 - 22518192
SN - 1687-9767
VL - 2012
JO - International Journal of Peptides
JF - International Journal of Peptides
M1 - 532519
ER -