TY - JOUR
T1 - Nano based drug delivery systems
T2 - Recent developments and future prospects
AU - Patra, Jayanta Kumar
AU - Das, Gitishree
AU - Fraceto, Leonardo Fernandes
AU - Campos, Estefania Vangelie Ramos
AU - Rodriguez-Torres, Maria Del Pilar
AU - Acosta-Torres, Laura Susana
AU - Diaz-Torres, Luis Armando
AU - Grillo, Renato
AU - Swamy, Mallappa Kumara
AU - Sharma, Shivesh
AU - Habtemariam, Solomon
AU - Shin, Han Seung
N1 - Publisher Copyright:
© 2018 The Author(s).
PY - 2018/9/19
Y1 - 2018/9/19
N2 - Nanomedicine and nano delivery systems are a relatively new but rapidly developing science where materials in the nanoscale range are employed to serve as means of diagnostic tools or to deliver therapeutic agents to specific targeted sites in a controlled manner. Nanotechnology offers multiple benefits in treating chronic human diseases by site-specific, and target-oriented delivery of precise medicines. Recently, there are a number of outstanding applications of the nanomedicine (chemotherapeutic agents, biological agents, immunotherapeutic agents etc.) in the treatment of various diseases. The current review, presents an updated summary of recent advances in the field of nanomedicines and nano based drug delivery systems through comprehensive scrutiny of the discovery and application of nanomaterials in improving both the efficacy of novel and old drugs (e.g., natural products) and selective diagnosis through disease marker molecules. The opportunities and challenges of nanomedicines in drug delivery from synthetic/natural sources to their clinical applications are also discussed. In addition, we have included information regarding the trends and perspectives in nanomedicine area.
AB - Nanomedicine and nano delivery systems are a relatively new but rapidly developing science where materials in the nanoscale range are employed to serve as means of diagnostic tools or to deliver therapeutic agents to specific targeted sites in a controlled manner. Nanotechnology offers multiple benefits in treating chronic human diseases by site-specific, and target-oriented delivery of precise medicines. Recently, there are a number of outstanding applications of the nanomedicine (chemotherapeutic agents, biological agents, immunotherapeutic agents etc.) in the treatment of various diseases. The current review, presents an updated summary of recent advances in the field of nanomedicines and nano based drug delivery systems through comprehensive scrutiny of the discovery and application of nanomaterials in improving both the efficacy of novel and old drugs (e.g., natural products) and selective diagnosis through disease marker molecules. The opportunities and challenges of nanomedicines in drug delivery from synthetic/natural sources to their clinical applications are also discussed. In addition, we have included information regarding the trends and perspectives in nanomedicine area.
KW - Drug delivery
KW - Drug targeting
KW - Nanomaterials
KW - Nanomedicine
KW - Natural products
UR - http://www.scopus.com/inward/record.url?scp=85053681127&partnerID=8YFLogxK
U2 - 10.1186/s12951-018-0392-8
DO - 10.1186/s12951-018-0392-8
M3 - Artículo de revisión
C2 - 30231877
SN - 1477-3155
VL - 16
JO - Journal of Nanobiotechnology
JF - Journal of Nanobiotechnology
IS - 1
M1 - 71
ER -
