Herramientas moleculares para el combate de la oncocercosis en México

Producción científica: Contribución a una revistaArtículo de revisiónrevisión exhaustiva

1 Cita (Scopus)

Resumen

Onchocerciasis is one of the major causes of blindness in the World, with about 17.7 million infected, particularly in West Africa. In Mexico, onchocerciasis is also present and has been subjected to control since 1923. The standard diagnosis of onchocerciasis is by the detection of microfilariae by skin biopsy and transmission is evaluated by detection of Onchocerca volvulus larvae in the vector. Classically, this was carried out by manual dissection of Simulium ochraceum s.l. However, with the use of ivermectin, a drug that kills microfilariae but not the adult worms, the skin biopsy is becoming no longer useful for detecting microfilariae levels and due to the reduced transmission, fly dissection is no longer viable. The subject of this paper is to present the immunological and molecular techniques developed to supersede the skin biopsy and fly dissection, and their diagnostic ability to assess the impact of multiple bi-annual mass ivermectin treatments on O. volvulus transmission in Mexico.

Título traducido de la contribuciónMolecular tools for fighting onchocerciasis in Mexico
Idioma originalEspañol
Páginas (desde-hasta)112-129
Número de páginas18
PublicaciónRevista latinoamericana de microbiologia
Volumen47
N.º3-4
EstadoPublicada - 2005

Palabras clave

  • DNA
  • Diagnosis
  • Monitoring
  • Parasite
  • Worm

Huella

Profundice en los temas de investigación de 'Herramientas moleculares para el combate de la oncocercosis en México'. En conjunto forman una huella única.

Citar esto