Efecto hepatoprotector del micelio de Trametes versicolor en un modelo de ratón de la cepa NIH

Currently, there has been increasing the interest in compounds contains in fungi, because they have health bene_ts. Therefore, it was determined whether ethanol, extract, and their fractions (ethyl acetate and hexane), obtains from mycelium of Trametes versicolor prevents oxidative stress and tissue damage-caused by CCl₄ intoxication. The ethanol extract and sub-fractions were administered to NIH male mice. Subsequently, the liver was obtained for quantifying oxidative stress, redox environment, and histological damage. We found that extracts decreased oxidative stress, and they prevent cellular damage-caused by CCl₄. It is concluded that ethanol extract and its fractions (ethyl acetate and hexane) protect against acute liver damage.