Control of multiplicative noise stochastic gene regulation systems by the attractive ellipsoid technique

This article describes the application of the so-called attractive ellipsoidal method to solve the trajectory stabilization problem for a class of genetic network systems modelled by a stochastic model. The genetic network model is described by a stochastic quasi-linear system affected by additive and multiplicative noises simultaneously. The solution of the control design provided in this study is based on a linear feedback structure. In this paper the algorithm to construct a suboptimal gain for adjusting the control design is introduced. The attractive ellipsoidal method is the key stone for designing the so-called suboptimal gain. Moreover, the practical stability of the genetic network trajectories is demonstrated on the mean and in almost sure senses. Some numerical simulations show how a set of stochastic trajectories are stabilized by the controller suggested in this study and how the predicted ellipsoid region is achieved by these trajectories.