TY - JOUR
T1 - Case report
T2 - Extrapulmonary manifestations of COVID-19 and dengue coinfection
AU - Reyes-Ruiz, José Manuel
AU - Campuzano-Vences, Rosa
AU - Osuna-Ramos, Juan Fidel
AU - de Jesus-González, Luis Adrián
AU - Pérez-Méndez, María J.
AU - González-González, Crescencio
AU - Farfan-Morales, Carlos Noe
AU - Rivas-Tovar, Leticia
AU - Davila-González, Eduardo
AU - del Ángel, Rosa María
AU - Gutiérrez-Garduño, Aarón P.
AU - Villegas-Del Ángel, Enrique
AU - Zárate-Segura, Paola
AU - Bastida-González, Fernando
N1 - Publisher Copyright:
Copyright © 2021 by The American Society of Tropical Medicine and Hygiene
PY - 2021/8
Y1 - 2021/8
N2 - The risk of coronavirus disease 2019 (COVID-19) and dengue coinfection is increased in tropical countries; however, the extrapulmonary clinical manifestations have not been fully characterized. We report a 42-year-old woman whose clinical manifestations began with fever, diarrhea, headache, chest pain, myalgia, odynophagia, and arthralgia. Despite mild respiratory symptoms and normal chest computed tomography scan results, she was diagnosed with real-time reverse-transcription polymerase chain reaction (RT-PCR)-confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Because she had erythema and petechiae with a decreased platelet count, the dengue NS1 antigen and anti-dengue IgM/IgG test were performed, and the Centers for Disease Control and Prevention RT-PCR assay detected the dengue virus serotype 1 infection. Additionally, increased liver enzyme serum levels were found in the patient, who later developed hepatomegaly. Hence, the mechanism of hepatic pathology associated with SARS-CoV-2 and dengue coinfection needs further research.
AB - The risk of coronavirus disease 2019 (COVID-19) and dengue coinfection is increased in tropical countries; however, the extrapulmonary clinical manifestations have not been fully characterized. We report a 42-year-old woman whose clinical manifestations began with fever, diarrhea, headache, chest pain, myalgia, odynophagia, and arthralgia. Despite mild respiratory symptoms and normal chest computed tomography scan results, she was diagnosed with real-time reverse-transcription polymerase chain reaction (RT-PCR)-confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Because she had erythema and petechiae with a decreased platelet count, the dengue NS1 antigen and anti-dengue IgM/IgG test were performed, and the Centers for Disease Control and Prevention RT-PCR assay detected the dengue virus serotype 1 infection. Additionally, increased liver enzyme serum levels were found in the patient, who later developed hepatomegaly. Hence, the mechanism of hepatic pathology associated with SARS-CoV-2 and dengue coinfection needs further research.
UR - http://www.scopus.com/inward/record.url?scp=85112858757&partnerID=8YFLogxK
U2 - 10.4269/ajtmh.21-0177
DO - 10.4269/ajtmh.21-0177
M3 - Artículo
C2 - 34181577
AN - SCOPUS:85112858757
SN - 0002-9637
VL - 105
SP - 363
EP - 397
JO - American Journal of Tropical Medicine and Hygiene
JF - American Journal of Tropical Medicine and Hygiene
IS - 2
ER -