Biotransformation of diterpenes

María Rico-Martínez, Fernanda G. Medina, Joaquín G. Marrero, Soraya Osegueda-Robles

Resultado de la investigación: Contribución a una revistaReseña científicarevisión exhaustiva

22 Citas (Scopus)

Resumen

Diterpenes are a versatile group of biologically active ingredients present in several phytoextracts. Structural modification of the diterpenes to enhance their pharmaceutical relevance can be efficiently carried out by the application of biotransformational processes using microorganisms or isolated enzymes. Over the past years, special attention has been paid to the biotransformation of diterpenes due to the fact that biocatalysts allow the production of enantiomerically pure compounds using mild and environmentally friendly processes. A wide range of microorganisms have been assessed for these biotransformations and have produced encouraging results, as discussed in this review. This report reviews reactions mediated by fungi, published between 2000 and 2013. © 2014 The Royal Society of Chemistry.
Idioma originalInglés estadounidense
Páginas (desde-hasta)10627-10647
Número de páginas9562
PublicaciónRSC Advances
DOI
EstadoPublicada - 28 feb 2014

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