Biomedical applications of magnetite nanoparticles

Greter Ortega, Edilso Reguera

Producción científica: Capítulo del libro/informe/acta de congresoCapítulorevisión exhaustiva

16 Citas (Scopus)

Resumen

This chapter contains an overview of biomedical applications of magnetite nanoparticles. In these areas, the physical-chemical particle features determine their biological behavior/fate and their potential applications. For this reason, the first part of this contribution briefly summarizes the available methods for iron oxide nanoparticles preparation, with an emphasis on magnetite, and their stabilizing procedures with further surface modification, that allows the subsequent conjugation to biomolecules and to guarantee nanoparticle biocompatibility. Hence, the available protocols of conjugation to biomolecules are briefly discussed considering the coordination chemistry according to the nanoparticle surface modifiers. The biomedical applications of magnetite nanoparticles herein considered, as well as their application basic principles, include: drug delivery, chemotherapy, magnetofection, hyperthermia, scaffold-based tissue engineering, MRI contrast agents, organ/tissue imaging, theranostic platforms, in vitro bioseparation, bioanalysis, and immunoassays.

Idioma originalInglés
Título de la publicación alojadaMaterials for Biomedical Engineering
Subtítulo de la publicación alojadaNanomaterials-based Drug Delivery
EditorialElsevier
Páginas397-434
Número de páginas38
ISBN (versión digital)9780128169131
DOI
EstadoPublicada - 1 ene. 2019

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