TY - JOUR
T1 - Antioxidant, antinociceptive, and anti-inflammatory effects of carotenoids extracted from dried pepper (Capsicum annuum L.)
AU - Hernández-Ortega, Marcela
AU - Ortiz-Moreno, Alicia
AU - Hernández-Navarro, María Dolores
AU - Chamorro-Cevallos, Germán
AU - Dorantes-Alvarez, Lidia
AU - Necoechea-Mondragón, Hugo
PY - 2012
Y1 - 2012
N2 - Carotenoids extracted from dried peppers were evaluated for their antioxidant, analgesic, and anti-inflammatory activities. Peppers had a substantial carotenoid content: guajillo 3406 ± 4 g/g, pasilla 2933 ± 1 g/g, and ancho 1437 ± 6 g/g of sample in dry weight basis. A complex mixture of carotenoids was discovered in each pepper extract. The TLC analysis revealed the presence of chlorophylls in the pigment extract from pasilla and ancho peppers. Guajillo pepper carotenoid extracts exhibited good antioxidant activity and had the best scavenging capacity for the DPPH + cation (24.2%). They also exhibited significant peripheral analgesic activity at 5, 20, and 80 mg/kg and induced central analgesia at 80 mg/kg. The results suggest that the carotenoids in dried guajillo peppers have significant analgesic and anti-inflammatory benefits and could be useful for pain and inflammation relief.
AB - Carotenoids extracted from dried peppers were evaluated for their antioxidant, analgesic, and anti-inflammatory activities. Peppers had a substantial carotenoid content: guajillo 3406 ± 4 g/g, pasilla 2933 ± 1 g/g, and ancho 1437 ± 6 g/g of sample in dry weight basis. A complex mixture of carotenoids was discovered in each pepper extract. The TLC analysis revealed the presence of chlorophylls in the pigment extract from pasilla and ancho peppers. Guajillo pepper carotenoid extracts exhibited good antioxidant activity and had the best scavenging capacity for the DPPH + cation (24.2%). They also exhibited significant peripheral analgesic activity at 5, 20, and 80 mg/kg and induced central analgesia at 80 mg/kg. The results suggest that the carotenoids in dried guajillo peppers have significant analgesic and anti-inflammatory benefits and could be useful for pain and inflammation relief.
UR - http://www.scopus.com/inward/record.url?scp=84871824879&partnerID=8YFLogxK
U2 - 10.1155/2012/524019
DO - 10.1155/2012/524019
M3 - Artículo
C2 - 23091348
SN - 1110-7243
VL - 2012
JO - Journal of Biomedicine and Biotechnology
JF - Journal of Biomedicine and Biotechnology
M1 - 524019
ER -