TY - JOUR
T1 - Antifeedant and Phytotoxic Activity of Hydroxyperezone and Related Molecules
AU - Burgueño-Tapia, Eleuterio
AU - Gonzélez-Coloma, Azucena
AU - Castillo, Lucía
AU - Joseph-Nathan, Pedro
N1 - Funding Information:
This work was supported by SIP-IPN, CONA-CYT, DGI (CTQ2006-15597-C02-01/PPQ), CYTED and an AECI fellowship to L. Castillo.We gratefully acknowledge S. Carlin for language revision.
PY - 2008/4
Y1 - 2008/4
N2 - The insect antifeedant and toxic activity of hydroxyperezone (1), its derivatives 2-9, along with 3-hydroxy- (10) and 6-hydroxythymoquinone (11) were studied against Spodoptera littoralis, Leptinotarsa decemlineata, and Myzus persicae. The antifeedant tests showed that L. decemlineata was the most sensitive insect, followed by M. persicae, while S. littoralis was not deterred by compounds 1-11. Leucohydroxyperezone tetraacetate (3), oxoperezinone (6), dihydroleucoperezinone diacetate (7), 3-hydroxy- (10) and 6-hydroxythymoquinone (11) showed strong activity against L. decemlineata. 1 and 7 exhibited moderate deterrent activity against M. persicae, while 1 and dihydroleucohydroxyperezone tetraacetate (4) acted as post-ingestive antifeedants to S. littoralis. The phytotoxic activity of compounds 1- 11 was also evaluated. Hydroxyperezone (1) strongly inhibited seed germination at 24 h, while the activity of 3-8 and 10 was moderate. The level of radicle growth inhibition obtained with compounds 1-5 and 8-11 was significant (< 50%).
AB - The insect antifeedant and toxic activity of hydroxyperezone (1), its derivatives 2-9, along with 3-hydroxy- (10) and 6-hydroxythymoquinone (11) were studied against Spodoptera littoralis, Leptinotarsa decemlineata, and Myzus persicae. The antifeedant tests showed that L. decemlineata was the most sensitive insect, followed by M. persicae, while S. littoralis was not deterred by compounds 1-11. Leucohydroxyperezone tetraacetate (3), oxoperezinone (6), dihydroleucoperezinone diacetate (7), 3-hydroxy- (10) and 6-hydroxythymoquinone (11) showed strong activity against L. decemlineata. 1 and 7 exhibited moderate deterrent activity against M. persicae, while 1 and dihydroleucohydroxyperezone tetraacetate (4) acted as post-ingestive antifeedants to S. littoralis. The phytotoxic activity of compounds 1- 11 was also evaluated. Hydroxyperezone (1) strongly inhibited seed germination at 24 h, while the activity of 3-8 and 10 was moderate. The level of radicle growth inhibition obtained with compounds 1-5 and 8-11 was significant (< 50%).
KW - Antifeedant
KW - Hydroxyperezone Derivatives
KW - Phytotoxicity
UR - http://www.scopus.com/inward/record.url?scp=45849139827&partnerID=8YFLogxK
U2 - 10.1515/znc-2008-3-411
DO - 10.1515/znc-2008-3-411
M3 - Artículo
SN - 0939-5075
VL - 63
SP - 221
EP - 225
JO - Zeitschrift fur Naturforschung - Section C Journal of Biosciences
JF - Zeitschrift fur Naturforschung - Section C Journal of Biosciences
IS - 3-4
ER -