TY - JOUR
T1 - An alternative hepatoprotective and antioxidant agent
T2 - The Geranium
AU - Bautista, Mirandeli
AU - Madrigal-Santillán, Eduardo
AU - Morales-González, Ángel
AU - Gayosso-Delucio, Juan A.
AU - Madrigal-Bujaidar, Eduardo
AU - Chamorro-Cevallos, German
AU - Álvarez-González, Isela
AU - Benedi, Juana
AU - Aguilar-Faisal, J. Leopoldo
AU - Morales-González, José A.
N1 - Publisher Copyright:
© 2015, African Ethnomedicines Network. All rights reserved.
PY - 2015
Y1 - 2015
N2 - Background: The Geranium genus is taxonomically classified within the family Geraniaceae Juss, which includes 5-11 genera and nearly 750 species in total. The best-known genera of this family are Geranium, consisting largely of wild plants, and Pelargonium, consisting largely of ornamental plants. Traditional uses include as an antiseptic in wounds and as an antipyretic by infusion of the plant. Methods: This paper summarized previous and recent reports of the hepato-protective activities of Geranium genus used in traditional medicine. Results: Currently, eight different species of geraniums belonging to the family Geraniaceae have been identified in Hidalgo State in Central Mexico, and no chemical or pharmacological studies have been carried out in any of these eight species. All phytochemical studies on these species indicate the presence of polyphenolic compounds, including tannins, which are characterized as water-soluble compounds with molecular weights between 500 and 30,000 g/mol. Conclusion: These and other compounds warrant the exploration of the Germanium genus for uses related to ethanol-induced hepatotoxicity.
AB - Background: The Geranium genus is taxonomically classified within the family Geraniaceae Juss, which includes 5-11 genera and nearly 750 species in total. The best-known genera of this family are Geranium, consisting largely of wild plants, and Pelargonium, consisting largely of ornamental plants. Traditional uses include as an antiseptic in wounds and as an antipyretic by infusion of the plant. Methods: This paper summarized previous and recent reports of the hepato-protective activities of Geranium genus used in traditional medicine. Results: Currently, eight different species of geraniums belonging to the family Geraniaceae have been identified in Hidalgo State in Central Mexico, and no chemical or pharmacological studies have been carried out in any of these eight species. All phytochemical studies on these species indicate the presence of polyphenolic compounds, including tannins, which are characterized as water-soluble compounds with molecular weights between 500 and 30,000 g/mol. Conclusion: These and other compounds warrant the exploration of the Germanium genus for uses related to ethanol-induced hepatotoxicity.
KW - Ethanol
KW - Geranium
KW - Polyphenolic compounds
KW - Tannins
UR - http://www.scopus.com/inward/record.url?scp=84938584276&partnerID=8YFLogxK
U2 - 10.4314/ajtcam.v12i4.15
DO - 10.4314/ajtcam.v12i4.15
M3 - Artículo
SN - 0189-6016
VL - 12
SP - 96
EP - 105
JO - African journal of traditional, complementary, and alternative medicines : AJTCAM
JF - African journal of traditional, complementary, and alternative medicines : AJTCAM
IS - 4
ER -