TY - JOUR
T1 - A Study of the Classical Asymptotic Noninferiority Test for Two Binomial Proportions
AU - Almendra-Arao, Fãlix
PY - 2009/9
Y1 - 2009/9
N2 - In a recent article by Li and Chuang-Stein (1), an evaluation was made of the performance of two frequently used methods—the classical asymptotic normal approximation and the same method with the Hauck-Anderson continuity correction—to test noninferiority between two proportions. The evaluation, using simulation, estimated type I errors and power. Continuing the research of Li and Chuang-Stein, this study evaluates the performance of these two methods. However, here type I errors are not estimated from simulation, and levels of significance are computed by enumerating all possible cases rather than through simulation. And finally, instead of the confidence intervals approach adopted in Li and Chuang-Stein, our work uses the hypothesis tests approach. The results show a comparison of the two methods that is different from that obtained by Li and Chuang-Stein.
AB - In a recent article by Li and Chuang-Stein (1), an evaluation was made of the performance of two frequently used methods—the classical asymptotic normal approximation and the same method with the Hauck-Anderson continuity correction—to test noninferiority between two proportions. The evaluation, using simulation, estimated type I errors and power. Continuing the research of Li and Chuang-Stein, this study evaluates the performance of these two methods. However, here type I errors are not estimated from simulation, and levels of significance are computed by enumerating all possible cases rather than through simulation. And finally, instead of the confidence intervals approach adopted in Li and Chuang-Stein, our work uses the hypothesis tests approach. The results show a comparison of the two methods that is different from that obtained by Li and Chuang-Stein.
KW - Binomial proportions
KW - Classical asymptotic
KW - Hypothesis test
KW - Noninferiority test
KW - Significance level
UR - http://www.scopus.com/inward/record.url?scp=84996166818&partnerID=8YFLogxK
U2 - 10.1177/009286150904300505
DO - 10.1177/009286150904300505
M3 - Artículo
SN - 2168-4790
VL - 43
SP - 567
EP - 571
JO - Therapeutic Innovation and Regulatory Science
JF - Therapeutic Innovation and Regulatory Science
IS - 5
ER -