TY - JOUR
T1 - A new germacranolide from Ageratina vernalis
AU - Fuentes-Figueroa, Miguel
AU - Tlapale-Lara, Neively
AU - Hernández-Carlos, Beatriz
AU - Joseph-Nathan, Pedro
AU - Burgueño-Tapia, Eleuterio
N1 - Publisher Copyright:
© 2020 Informa UK Limited, trading as Taylor & Francis Group.
PY - 2022
Y1 - 2022
N2 - The aerial parts of Ageratina vernalis provided the new germacranolide 1,10-epoxydeltoidin A (3), together with the known pentacyclic triterpenoid hopane-6α,22-diol (1), and the also known germacranolides deltoidin A (2) and 15-hydroxydeltoidin A (4). In addition, pTsOH catalyzed cyclization of 2 afforded the new guaianolide 5. The absolute configuration of 2, 4, and 5 was assigned by vibrational circular dichroism spectroscopy, while the complete 1H and 13C NMR data assignments of 2-5 followed from 1 D- and 2 D-NMR experiments.
AB - The aerial parts of Ageratina vernalis provided the new germacranolide 1,10-epoxydeltoidin A (3), together with the known pentacyclic triterpenoid hopane-6α,22-diol (1), and the also known germacranolides deltoidin A (2) and 15-hydroxydeltoidin A (4). In addition, pTsOH catalyzed cyclization of 2 afforded the new guaianolide 5. The absolute configuration of 2, 4, and 5 was assigned by vibrational circular dichroism spectroscopy, while the complete 1H and 13C NMR data assignments of 2-5 followed from 1 D- and 2 D-NMR experiments.
KW - Ageratina vernalis
KW - germacranolides
KW - vibrational circular dichroism
UR - http://www.scopus.com/inward/record.url?scp=85091838404&partnerID=8YFLogxK
U2 - 10.1080/14786419.2020.1827400
DO - 10.1080/14786419.2020.1827400
M3 - Artículo
C2 - 32998543
AN - SCOPUS:85091838404
SN - 1478-6419
VL - 36
SP - 2254
EP - 2262
JO - Natural Product Research
JF - Natural Product Research
IS - 9
ER -