A Convergent Total Synthesis of the Biologically Active Benzofurans Ailanthoidol, Egonol and Homoegonol from Biomass-Derived Eugenol

José C. Espinoza-Hicks; Gerardo Zaragoza-Galán; David Chávez-Flores; Víctor H. Ramos-Sánchez; Joaquín Tamariz; Alejandro A. Camacho-Dávila

doi:10.1055/s-0037-1610169

A Convergent Total Synthesis of the Biologically Active Benzofurans Ailanthoidol, Egonol and Homoegonol from Biomass-Derived Eugenol

José C. Espinoza-Hicks, Gerardo Zaragoza-Galán, David Chávez-Flores, Víctor H. Ramos-Sánchez, Joaquín Tamariz, Alejandro A. Camacho-Dávila

Escuela Nacional de Ciencias Biológicas (ENCB)

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2 Citas (Scopus)

Resumen

An efficient, general synthetic protocol for the synthesis of the biologically active benzofurans ailanthoidol, egonol and homoegonol was developed. The key starting material, eugenol, is a naturally occurring and abundant precursor. The protocol, involving sequential acylation and intramolecular Wittig reaction, provides a convenient method for building the benzofuran moiety in good yield.

Idioma original	Inglés
Número de artículo	ss-2018-m0239-op
Páginas (desde-hasta)	3493-3498
Número de páginas	6
Publicación	Synthesis (Germany)
Volumen	50
N.º	17
DOI	https://doi.org/10.1055/s-0037-1610169
Estado	Publicada - 2018

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10.1055/s-0037-1610169

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Espinoza-Hicks, J. C., Zaragoza-Galán, G., Chávez-Flores, D., Ramos-Sánchez, V. H., Tamariz, J., & Camacho-Dávila, A. A. (2018). A Convergent Total Synthesis of the Biologically Active Benzofurans Ailanthoidol, Egonol and Homoegonol from Biomass-Derived Eugenol. Synthesis (Germany), 50(17), 3493-3498. Artículo ss-2018-m0239-op. https://doi.org/10.1055/s-0037-1610169

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abstract = "An efficient, general synthetic protocol for the synthesis of the biologically active benzofurans ailanthoidol, egonol and homoegonol was developed. The key starting material, eugenol, is a naturally occurring and abundant precursor. The protocol, involving sequential acylation and intramolecular Wittig reaction, provides a convenient method for building the benzofuran moiety in good yield.",

keywords = "ailanthoidol, benzofurans, egonol, homoegonol, natural products, sustainable synthesis, total synthesis",

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year = "2018",

doi = "10.1055/s-0037-1610169",

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A Convergent Total Synthesis of the Biologically Active Benzofurans Ailanthoidol, Egonol and Homoegonol from Biomass-Derived Eugenol. / Espinoza-Hicks, José C.; Zaragoza-Galán, Gerardo; Chávez-Flores, David et al.
En: Synthesis (Germany), Vol. 50, N.º 17, ss-2018-m0239-op, 2018, p. 3493-3498.

Producción científica: Contribución a una revista › Artículo › revisión exhaustiva

TY - JOUR

T1 - A Convergent Total Synthesis of the Biologically Active Benzofurans Ailanthoidol, Egonol and Homoegonol from Biomass-Derived Eugenol

AU - Espinoza-Hicks, José C.

AU - Zaragoza-Galán, Gerardo

AU - Chávez-Flores, David

AU - Ramos-Sánchez, Víctor H.

AU - Tamariz, Joaquín

AU - Camacho-Dávila, Alejandro A.

PY - 2018

Y1 - 2018

N2 - An efficient, general synthetic protocol for the synthesis of the biologically active benzofurans ailanthoidol, egonol and homoegonol was developed. The key starting material, eugenol, is a naturally occurring and abundant precursor. The protocol, involving sequential acylation and intramolecular Wittig reaction, provides a convenient method for building the benzofuran moiety in good yield.

AB - An efficient, general synthetic protocol for the synthesis of the biologically active benzofurans ailanthoidol, egonol and homoegonol was developed. The key starting material, eugenol, is a naturally occurring and abundant precursor. The protocol, involving sequential acylation and intramolecular Wittig reaction, provides a convenient method for building the benzofuran moiety in good yield.

KW - ailanthoidol

KW - benzofurans

KW - egonol

KW - homoegonol

KW - natural products

KW - sustainable synthesis

KW - total synthesis

UR - http://www.scopus.com/inward/record.url?scp=85052198949&partnerID=8YFLogxK

U2 - 10.1055/s-0037-1610169

DO - 10.1055/s-0037-1610169

M3 - Artículo

SN - 0039-7881

VL - 50

SP - 3493

EP - 3498

JO - Synthesis (Germany)

JF - Synthesis (Germany)

IS - 17

M1 - ss-2018-m0239-op

ER -

A Convergent Total Synthesis of the Biologically Active Benzofurans Ailanthoidol, Egonol and Homoegonol from Biomass-Derived Eugenol

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