TY - JOUR
T1 - Volatile Profiling, Insecticidal, Antibacterial and Antiproliferative Properties of the Essential Oils of Bursera glabrifolia Leaves
AU - Villa-Ruano, Nemesio
AU - Becerra-Martínez, Elvia
AU - Cruz-Durán, Ramiro
AU - Zarate-Reyes, José Alejo
AU - Landeta-Cortés, Gerardo
AU - Romero-Arenas, Omar
N1 - Publisher Copyright:
© 2018 Wiley-VHCA AG, Zurich, Switzerland
PY - 2018/11
Y1 - 2018/11
N2 - The present article describes the chemical composition and biological activities of the essential oils of B. glabrifolia leaves obtained in four consecutive years (2015–2018). The essential oils contained α-terpineol (17.9–29.7 %), α-terpinene (12.6–17.4 %), limonene (14.9–26.8 %) and β-pinene (2.1–16.7 %) as the most abundant volatiles. The essential oils and these volatiles showed a significant adulticide activity (p<0.01; LC50 <100 μg mL−1) on the maize weevil (Sitophilus zeamais) with a 100 % mortality rate within a period of 5 h. Also, the essential oils showed a strong antibacterial activity on Enterococcus faecalis ATCC 29212 (MIC, 132.7–173.6 μg mL−1) and Helicobacter pylori ATCC 43504 (MIC, 74.8–199.2 μg mL−1). The assessment of the main volatiles revealed α-terpineol as the principal antibacterial agent (MIC, 78.6–149.7 μg mL−1). Similarly, the essential oils exhibited a substantial in vitro antiproliferative activity on the human prostate cancer cell lines PC-3 (LC50, 15.2–19.4 μg mL−1), the human ovarian carcinoma cell lines OVCAR-3 (LC50, 27.3–53.7 μg mL−1) and the myelogenous leukemia cell lines K-562 (LC50, 32.4–75.9 μg mL−1). α-Terpineol (LC50, 32.4–75.9 μg mL−1) exhibited the strongest antiproliferative effect on these cancer cell lines (LC50, 22.4–48.1 μg mL−1).
AB - The present article describes the chemical composition and biological activities of the essential oils of B. glabrifolia leaves obtained in four consecutive years (2015–2018). The essential oils contained α-terpineol (17.9–29.7 %), α-terpinene (12.6–17.4 %), limonene (14.9–26.8 %) and β-pinene (2.1–16.7 %) as the most abundant volatiles. The essential oils and these volatiles showed a significant adulticide activity (p<0.01; LC50 <100 μg mL−1) on the maize weevil (Sitophilus zeamais) with a 100 % mortality rate within a period of 5 h. Also, the essential oils showed a strong antibacterial activity on Enterococcus faecalis ATCC 29212 (MIC, 132.7–173.6 μg mL−1) and Helicobacter pylori ATCC 43504 (MIC, 74.8–199.2 μg mL−1). The assessment of the main volatiles revealed α-terpineol as the principal antibacterial agent (MIC, 78.6–149.7 μg mL−1). Similarly, the essential oils exhibited a substantial in vitro antiproliferative activity on the human prostate cancer cell lines PC-3 (LC50, 15.2–19.4 μg mL−1), the human ovarian carcinoma cell lines OVCAR-3 (LC50, 27.3–53.7 μg mL−1) and the myelogenous leukemia cell lines K-562 (LC50, 32.4–75.9 μg mL−1). α-Terpineol (LC50, 32.4–75.9 μg mL−1) exhibited the strongest antiproliferative effect on these cancer cell lines (LC50, 22.4–48.1 μg mL−1).
KW - B. glabrifolia
KW - antibacterial activity
KW - antiproliferative activity
KW - biological activity
KW - cytotoxicity
KW - essential oil
KW - insecticidal activity
UR - http://www.scopus.com/inward/record.url?scp=85055578455&partnerID=8YFLogxK
U2 - 10.1002/cbdv.201800354
DO - 10.1002/cbdv.201800354
M3 - Artículo
C2 - 30187618
SN - 1612-1872
VL - 15
JO - Chemistry and Biodiversity
JF - Chemistry and Biodiversity
IS - 11
M1 - e1800354
ER -