Factores de transferencia en la terapéutica médica

Dolores J. Sánchez-González; Carlos A. Sosa-Luna; Ismael Vásquez-Moctezuma

doi:10.1016/j.medcli.2010.05.002

Factores de transferencia en la terapéutica médica

Translated title of the contribution: Transfer factors in medical therapy

Dolores J. Sánchez-González, Carlos A. Sosa-Luna, Ismael Vásquez-Moctezuma

Escuela Superior de Medicina (ESM)

Research output: Contribution to journal › Review article › peer-review

10 Scopus citations

Abstract

Transfer factor (TF) consists of messenger peptides produced by activated T lymphocytes as part of cellular immunity, and it acts in virgin lymphocytes through TF inducers, suppressors and specific antigens. TF is not immunogenic because it is not species-specific, since it contains a consensus sequence of amino acids LLYAQDL/VEDN. TF extracted from leukocytes can transfer immunity from a human to another species. TF extracts are complex, containing more than 200 molecules with molecular weights ranging from 1 to 20 kDa. The antigen specific transfer factors (STF) have molecular weights between 3,5 and 5 kDa. TF is easy to prepare and well tolerated. It does not contain HL-A antigens against potential receptors and it can used as adjuvant therapy in several diseases.

Translated title of the contribution	Transfer factors in medical therapy
Original language	Spanish
Pages (from-to)	273-277
Number of pages	5
Journal	Medicina Clinica
Volume	137
Issue number	6
DOIs	https://doi.org/10.1016/j.medcli.2010.05.002
State	Published - 10 Sep 2011

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title = "Factores de transferencia en la terap{\'e}utica m{\'e}dica",

abstract = "Transfer factor (TF) consists of messenger peptides produced by activated T lymphocytes as part of cellular immunity, and it acts in virgin lymphocytes through TF inducers, suppressors and specific antigens. TF is not immunogenic because it is not species-specific, since it contains a consensus sequence of amino acids LLYAQDL/VEDN. TF extracted from leukocytes can transfer immunity from a human to another species. TF extracts are complex, containing more than 200 molecules with molecular weights ranging from 1 to 20 kDa. The antigen specific transfer factors (STF) have molecular weights between 3,5 and 5 kDa. TF is easy to prepare and well tolerated. It does not contain HL-A antigens against potential receptors and it can used as adjuvant therapy in several diseases.",

keywords = "Cancer, Immunotherapy, Transfer factor",

author = "S{\'a}nchez-Gonz{\'a}lez, {Dolores J.} and Sosa-Luna, {Carlos A.} and Ismael V{\'a}squez-Moctezuma",

year = "2011",

month = sep,

day = "10",

doi = "10.1016/j.medcli.2010.05.002",

language = "Espa{\~n}ol",

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TY - JOUR

T1 - Factores de transferencia en la terapéutica médica

AU - Sánchez-González, Dolores J.

AU - Sosa-Luna, Carlos A.

AU - Vásquez-Moctezuma, Ismael

PY - 2011/9/10

Y1 - 2011/9/10

N2 - Transfer factor (TF) consists of messenger peptides produced by activated T lymphocytes as part of cellular immunity, and it acts in virgin lymphocytes through TF inducers, suppressors and specific antigens. TF is not immunogenic because it is not species-specific, since it contains a consensus sequence of amino acids LLYAQDL/VEDN. TF extracted from leukocytes can transfer immunity from a human to another species. TF extracts are complex, containing more than 200 molecules with molecular weights ranging from 1 to 20 kDa. The antigen specific transfer factors (STF) have molecular weights between 3,5 and 5 kDa. TF is easy to prepare and well tolerated. It does not contain HL-A antigens against potential receptors and it can used as adjuvant therapy in several diseases.

AB - Transfer factor (TF) consists of messenger peptides produced by activated T lymphocytes as part of cellular immunity, and it acts in virgin lymphocytes through TF inducers, suppressors and specific antigens. TF is not immunogenic because it is not species-specific, since it contains a consensus sequence of amino acids LLYAQDL/VEDN. TF extracted from leukocytes can transfer immunity from a human to another species. TF extracts are complex, containing more than 200 molecules with molecular weights ranging from 1 to 20 kDa. The antigen specific transfer factors (STF) have molecular weights between 3,5 and 5 kDa. TF is easy to prepare and well tolerated. It does not contain HL-A antigens against potential receptors and it can used as adjuvant therapy in several diseases.

KW - Cancer

KW - Immunotherapy

KW - Transfer factor

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U2 - 10.1016/j.medcli.2010.05.002

DO - 10.1016/j.medcli.2010.05.002

M3 - Artículo de revisión

C2 - 20561650

SN - 0025-7753

VL - 137

SP - 273

EP - 277

JO - Medicina Clinica

JF - Medicina Clinica

IS - 6

ER -

Factores de transferencia en la terapéutica médica

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