The number and organization of the rRNA genes of several strains of Mycobacterium simiae

Sandra Rivera-Gutiérrez, Ernesto Montoro-Cardoso, Jose A. Valdivia, Robert A. Cox, Jorge A. Gonzalez-Y-Merchand

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The type strain of Mycobacterium simiae and four Cuban strains, each representing a group of variants sharing a characteristic pattern of glycopeptidolipids, were investigated. Each of the five strains was found to have a single rRNA (rrn) operon per genome. Each rrn operon was found to be located downstream from murA. Unusually for slow-growing mycobacteria, three transcription start points were identified for each operon. Gene sequences were established extending from near to the 3′-ends of murA, the intergenic regions and the 5′-ends of the 16S rDNAs. Characteristic strain differences were identified. © 2003 Federation of European Microbiological Societies. Published by Elsevier B.V. All rights reserved.
Original languageAmerican English
Pages (from-to)133-139
Number of pages7
JournalFEMS Microbiology Letters
StatePublished - 10 Oct 2003


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