TY - JOUR
T1 - Synthesis of novel polysubstituted N-benzyl-1H-pyrroles via a cascade reaction of alkynyl Fischer carbenes with α-imino glycine methyl esters
AU - De La Cruz, Fabiola N.
AU - López, Julio
AU - Jiménez-Halla, J. Óscar C.
AU - Flores-Álamo, Marcos
AU - Tamaríz, Joaquín
AU - Delgado, Francisco
AU - Vázquez, Miguel A.
N1 - Publisher Copyright:
© The Royal Society of Chemistry.
PY - 2015/10/13
Y1 - 2015/10/13
N2 - An efficient and simple synthesis of novel and densely substituted N-benzyl-1H-pyrroles 6a-r is described by a 1,4-addition/isomerization/ring closure/demetalation cascade process of alkynyl Fischer carbene complexes 1a-f and 2a and α-imino glycine methyl esters 3a, b, d, g, h, and k promoted with LDA.
AB - An efficient and simple synthesis of novel and densely substituted N-benzyl-1H-pyrroles 6a-r is described by a 1,4-addition/isomerization/ring closure/demetalation cascade process of alkynyl Fischer carbene complexes 1a-f and 2a and α-imino glycine methyl esters 3a, b, d, g, h, and k promoted with LDA.
UR - http://www.scopus.com/inward/record.url?scp=84948660645&partnerID=8YFLogxK
U2 - 10.1039/c5ob01655j
DO - 10.1039/c5ob01655j
M3 - Artículo
C2 - 26488365
SN - 1477-0520
VL - 13
SP - 11753
EP - 11760
JO - Organic and Biomolecular Chemistry
JF - Organic and Biomolecular Chemistry
IS - 48
ER -