TY - JOUR
T1 - Synthesis, Kinetic Study, and Spectroscopic Analysis of Peroxidase-like Pinch-Porphyrin Fe(III) Complexes
AU - Vazquez-Lima, Hugo
AU - Arroyo Abad, Uriel
AU - Pérez Benítez, Aarón
AU - Ramírez Rosales, Daniel
AU - Zamorano Ulloa, Rafael
AU - Reyes Ortega, Yasmi
AU - Hernández Anzaldo, Samuel
N1 - Publisher Copyright:
Copyright © 2019 American Chemical Society.
PY - 2019/12/31
Y1 - 2019/12/31
N2 - In the present manuscript, we report the kinetic and spectroscopic analysis of six new pinch-porphyrins: Protoporphyrin-picpenta 1, mesoporphyrin-picpenta 2, deuteroporphyrin-picpenta 3, protoporphyrin-picocta 4, mesoporphyrin-picocta 5, and deuteroporphyrin-picocta 6. The Michaelis-Menten enzymatic pathway and the guaiacol test confirmed the ability of the compounds to function like new peroxidase models. UV-vis, 1H NMR, and electron spin resonance studies are in accordance with porphyrin-Fe(III) molecules with the quantum phenomena called quantum mixed spin (qms, s = 3/2, s = 5/2). Importantly, the influence of the presence of the s = 3/2 spin state in the compounds and its critical role for the catalytic capacity is proven here, which was the original hypothesis in our research group. The compounds with higher populations of the s = 3/2 spin state have increased peroxidase activity.
AB - In the present manuscript, we report the kinetic and spectroscopic analysis of six new pinch-porphyrins: Protoporphyrin-picpenta 1, mesoporphyrin-picpenta 2, deuteroporphyrin-picpenta 3, protoporphyrin-picocta 4, mesoporphyrin-picocta 5, and deuteroporphyrin-picocta 6. The Michaelis-Menten enzymatic pathway and the guaiacol test confirmed the ability of the compounds to function like new peroxidase models. UV-vis, 1H NMR, and electron spin resonance studies are in accordance with porphyrin-Fe(III) molecules with the quantum phenomena called quantum mixed spin (qms, s = 3/2, s = 5/2). Importantly, the influence of the presence of the s = 3/2 spin state in the compounds and its critical role for the catalytic capacity is proven here, which was the original hypothesis in our research group. The compounds with higher populations of the s = 3/2 spin state have increased peroxidase activity.
UR - http://www.scopus.com/inward/record.url?scp=85078786340&partnerID=8YFLogxK
U2 - 10.1021/acsomega.9b03186
DO - 10.1021/acsomega.9b03186
M3 - Artículo
C2 - 31909335
SN - 2470-1343
VL - 4
SP - 22521
EP - 22529
JO - ACS Omega
JF - ACS Omega
IS - 27
ER -