Abstract
(Figure presented) An efficient and versatile synthesis of novel exo-imidazolidin-2-one dienes is described. This involves the base-assisted condensation/cyclization cascade reaction of the monoimino derivatives of diacetyl with a series of isocyanates. This methodology enables preparation of symmetrical dienes, as long as the substrates have the same N substituent. Moreover, use of different N-substituted starting materials leads to formation of nonsymmetrical dienes. The reactivity of these dienes was evaluated in Diels - Alder reactions, showing a high reactivity.
Original language | English |
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Pages (from-to) | 7901-7911 |
Number of pages | 11 |
Journal | Journal of Organic Chemistry |
Volume | 76 |
Issue number | 19 |
DOIs | |
State | Published - 7 Oct 2011 |