TY - JOUR
T1 - Synthesis and characterization of glycerol citrate polymer and yttrium oxide nanoparticles as a potential antibacterial material
AU - Mariano-Torres, Jaime Alfredo
AU - López-Marure, Arturo
AU - García-Hernández, Margarita
AU - Basurto-Islas, Gustavo
AU - Domínguez-Sánchez, Miguel Ángel
N1 - Publisher Copyright:
© 2018 The Japan Institute of Metals and Materials.
PY - 2018
Y1 - 2018
N2 - The synthesis of a new hybrid polymer derived from glycerol citrate polymer (GCP) and yttrium oxide nanoparticles was performed without catalyst and using an equimolar concentration. The biocompatibility and antimicrobial capacity of citrate-based polymers suggest it to be involved in biomedical applications since citric acid is a natural molecule. Glycerol citrate polymer and yttrium oxide (Y2O3) nanoparticles were synthesized by autocatalytic polymerization and sol-gel methods respectively. Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), transmission electron microscopy (TEM), differential scanning calorimetry (DSC), antibacterial effect and cell viability assay were performed to characterize the material. The cubic crystalline Y2O3 nanoparticles dispersed in glycerol citrate polymer could be the cause of the increased antibacterial effect presented in the pure glycerol citrate polymer; supporting the potential of the hybrid polymer as a biotechnological material. The cytotoxicity was evaluated trough human neuroblastoma SH-SY5Y cell.
AB - The synthesis of a new hybrid polymer derived from glycerol citrate polymer (GCP) and yttrium oxide nanoparticles was performed without catalyst and using an equimolar concentration. The biocompatibility and antimicrobial capacity of citrate-based polymers suggest it to be involved in biomedical applications since citric acid is a natural molecule. Glycerol citrate polymer and yttrium oxide (Y2O3) nanoparticles were synthesized by autocatalytic polymerization and sol-gel methods respectively. Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), transmission electron microscopy (TEM), differential scanning calorimetry (DSC), antibacterial effect and cell viability assay were performed to characterize the material. The cubic crystalline Y2O3 nanoparticles dispersed in glycerol citrate polymer could be the cause of the increased antibacterial effect presented in the pure glycerol citrate polymer; supporting the potential of the hybrid polymer as a biotechnological material. The cytotoxicity was evaluated trough human neuroblastoma SH-SY5Y cell.
KW - Antibacterial effect
KW - Biotechnology
KW - Nanoparticles
KW - Polymers
UR - http://www.scopus.com/inward/record.url?scp=85057457430&partnerID=8YFLogxK
U2 - 10.2320/matertrans.M2018248
DO - 10.2320/matertrans.M2018248
M3 - Artículo
AN - SCOPUS:85057457430
SN - 1345-9678
VL - 59
SP - 1915
EP - 1919
JO - Materials Transactions
JF - Materials Transactions
IS - 12
ER -