TY - JOUR
T1 - Surface modification of the Ti-6Al-4V alloy by anodic oxidation and its effect on osteoarticular cell proliferation
AU - Torres-Avila, Itzel P.
AU - Padilla-Martínez, Itzia I.
AU - Pérez-Hernández, Nury
AU - Bañuelos-Hernández, Angel E.
AU - Velázquez, Julio C.
AU - Castrejón-Flores, José L.
AU - Hernández-Sánchez, Enrique
N1 - Publisher Copyright:
© 2020 by the authors.
PY - 2020/5/1
Y1 - 2020/5/1
N2 - This investigation describes the formation of crystalline nanotubes of titanium oxide on the surface of a Ti-6Al-4V alloy and its biological evaluation. The formation of nanotubes was performed by the anodic oxidation technique with a constant work potential of 60 V but with different anodizing times of 10, 20, 30, 40, 50, and 60 min used to evaluate their effects on the characteristics of the nanotubes and their biological activity. A mixture of ethylene glycol, water, and ammonium fluoride (NH4F) was used as the electrolytic fluid. Scanning electron microscopy (SEM) and X-ray diffraction (XRD) were applied to determine the morphology and crystalline nature of the nanotubes, showing a well-defined matrix of nanotubes of titanium oxide with a crystalline structure and a diameter in the range of 52.5 - 5.13 to 95 - 11.92 nm. In contrast, the XRD patterns showed an increase of defined peaks that directly correlated with treatment times. Moreover, in vitro assays using an innovative cell culture device demonstrated that the inner diameter of the nanotubes directly correlated with cell proliferation.
AB - This investigation describes the formation of crystalline nanotubes of titanium oxide on the surface of a Ti-6Al-4V alloy and its biological evaluation. The formation of nanotubes was performed by the anodic oxidation technique with a constant work potential of 60 V but with different anodizing times of 10, 20, 30, 40, 50, and 60 min used to evaluate their effects on the characteristics of the nanotubes and their biological activity. A mixture of ethylene glycol, water, and ammonium fluoride (NH4F) was used as the electrolytic fluid. Scanning electron microscopy (SEM) and X-ray diffraction (XRD) were applied to determine the morphology and crystalline nature of the nanotubes, showing a well-defined matrix of nanotubes of titanium oxide with a crystalline structure and a diameter in the range of 52.5 - 5.13 to 95 - 11.92 nm. In contrast, the XRD patterns showed an increase of defined peaks that directly correlated with treatment times. Moreover, in vitro assays using an innovative cell culture device demonstrated that the inner diameter of the nanotubes directly correlated with cell proliferation.
KW - Anodic oxidation
KW - Crystalline structure
KW - Surface modification
KW - Titanium nanotubes
UR - http://www.scopus.com/inward/record.url?scp=85086116664&partnerID=8YFLogxK
U2 - 10.3390/COATINGS10050491
DO - 10.3390/COATINGS10050491
M3 - Artículo
SN - 2079-6412
VL - 10
JO - Coatings
JF - Coatings
IS - 5
M1 - 491
ER -