Relative Stereochemistry and Absolute Configuration of Farinosin, a Eudesmanolide From Encelia farinosa

Alfredo R. Ortega, Mariano Sánchez-Castellanos, Nury Pérez-Hernández, Ramón E. Robles-Zepeda, Pedro Joseph-Nathan, Leovigildo Quijano

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

The naturally occurring eudesmanolide farinosin (1) is now fully characterized for the first time despite its original isolation almost half a century ago. The early assumed relative stereochemistry and absolute configuration were confirmed by vibrational circular dichroism together with evaluation of the Hooft X-ray parameters. The molecular conformation is very similar in the gas stage and in the solid state. Chirality 28:415–419, 2016.

Original languageEnglish
Pages (from-to)415-419
Number of pages5
JournalChirality
Volume28
Issue number5
DOIs
StatePublished - May 2016

Keywords

  • Hooft parameter
  • absolute configuration
  • relative stereochemistry
  • single crystal X-ray diffraction
  • vibrational circular dichroism

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