Regenerative treatment with umbilical cord mesenchymal stem cells from Wharton’s jelly in chronic ulcer caused by dermolipectomy

César M. Mejía-Barradas, Jaime E. Cázares-Montañez, Ángel Guerra-Márquez, Víctor G. Hernández-Chávez, Julio R. Cáceres-Cortés, Gisela Gutiérrez-Iglesias

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

© 2019 Publicaciones Permanyer. All rights reserved. Background: Procedures to remove adiposities and skin, such as dermolipectomy, can develop wounds that are difficult to heal by conventional therapies. Mesenchymal stem cells are indicated as potential candidates for regenerative therapy in wounds, due to their multipotentiality, low immunogenicity, modulating capacity of inflammation and tissue modeling processes. Case report: Patient with dehiscent chronic ulcer secondary to dermolipectomy, who received cutaneous treatment with mesenchymal stem cells. The therapy induced scar formation and neovascularization, as well as the decrease of infiltrated leukocytes and proinflammatory cytokines. Mesenchymal cells are proposed as an interesting alternative for the treatment of postoperative lesions.
Original languageAmerican English
Pages (from-to)8-16
Number of pages9
JournalCirugia y Cirujanos (English Edition)
DOIs
StatePublished - 1 Jan 2019

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