TY - JOUR
T1 - Tratamiento regenerativo con células madre mesenquimales provenientes de la gelatina de Wharton de cordón umbilical en la úlcera crónica por dermolipectomía
AU - Mejía-Barradas, César M.
AU - Cázares-Montañez, Jaime E.
AU - Guerra-Márquez, Ángel
AU - Hernández-Chávez, Víctor G.
AU - Cáceres-Cortés, Julio R.
AU - Gutiérrez-Iglesias, Gisela
N1 - Publisher Copyright:
© 2019 Publicaciones Permanyer. All rights reserved.
PY - 2019
Y1 - 2019
N2 - Background: Procedures to remove adiposities and skin, such as dermolipectomy, can develop wounds that are difficult to heal by conventional therapies. Mesenchymal stem cells are indicated as potential candidates for regenerative therapy in wounds, due to their multipotentiality, low immunogenicity, modulating capacity of inflammation and tissue modeling processes. Case report: Patient with dehiscent chronic ulcer secondary to dermolipectomy, who received cutaneous treatment with mesenchymal stem cells. The therapy induced scar formation and neovascularization, as well as the decrease of infiltrated leukocytes and proinflammatory cytokines. Mesenchymal cells are proposed as an interesting alternative for the treatment of postoperative lesions.
AB - Background: Procedures to remove adiposities and skin, such as dermolipectomy, can develop wounds that are difficult to heal by conventional therapies. Mesenchymal stem cells are indicated as potential candidates for regenerative therapy in wounds, due to their multipotentiality, low immunogenicity, modulating capacity of inflammation and tissue modeling processes. Case report: Patient with dehiscent chronic ulcer secondary to dermolipectomy, who received cutaneous treatment with mesenchymal stem cells. The therapy induced scar formation and neovascularization, as well as the decrease of infiltrated leukocytes and proinflammatory cytokines. Mesenchymal cells are proposed as an interesting alternative for the treatment of postoperative lesions.
KW - Chronic ulcer
KW - Dermolipectomy
KW - Inflammation
KW - Mesenchymal stem cells
KW - Regenerative medicine
KW - Scarring
UR - http://www.scopus.com/inward/record.url?scp=85071972198&partnerID=8YFLogxK
U2 - 10.24875/CIRU.18000515
DO - 10.24875/CIRU.18000515
M3 - Artículo
C2 - 31501623
AN - SCOPUS:85071972198
SN - 0009-7411
VL - 87
SP - 8
EP - 16
JO - Cirugia y Cirujanos (English Edition)
JF - Cirugia y Cirujanos (English Edition)
ER -