Possible association between preeclampsia-eclampsia and paternal age: A pilot study

Liliana García-Ortiz, José Gutiérrez-Salinas, Carlos Galaviz-Hernández, María del Carmen Chima-Galán, José M. Hilton-Cáceres, Fernando Escobedo-Aguirre, Marlene de la Peña-Gutiérrez, Antonio Iniesta-Mejía, Juan Miranda-Murillo

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Background: The preeclampsia is a multisystemic syndrome that occupied the first cause of maternal and fetal mortality around the world. Epidemiologic studies shown both mother and father contribute at the same risk for preeclampsia. Objective: To determinate if there is an association between preeclampsia and paternal age. Material and method: Preeclampsia-eclampsia patients and couples were analyzed in agree to "National High Blood Pressure Education Program Working Group" classification, and a control group constituted by normal pregnant women and couples was included. Results: There were 27 cases with mild preeclampsia and her couples, 13 cases with severe preeclampsia and her couples and 40 controls conformed by normal pregnant women and her couples. The statistical analysis of variance of the ages shown that men from preeclamptic group had a greater variance in contrast with man of control group (p < 0.001; valor of F = 5.084). Conclusions: Although is not clear how paternal age interview in preeclampsia risk, the interaction between paternal-maternal imprinting and spermatic senescence, followed by shortened telomeres of chromosome, could be produce the inactivity of a whole network of signals implicated in disease aetiology.
Original languageAmerican English
Pages (from-to)190-196
Number of pages170
JournalGinecologia y Obstetricia de Mexico
StatePublished - 1 Jan 2011

Fingerprint

Paternal Age
Eclampsia
Pre-Eclampsia
Pregnant Women
Mothers
Telomere Shortening
Fetal Mortality
Control Groups
Maternal Mortality
Fathers
Spermatozoa
Epidemiologic Studies
Analysis of Variance
Chromosomes
Interviews
Hypertension
Education

Cite this

García-Ortiz, L., Gutiérrez-Salinas, J., Galaviz-Hernández, C., Chima-Galán, M. D. C., Hilton-Cáceres, J. M., Escobedo-Aguirre, F., ... Miranda-Murillo, J. (2011). Possible association between preeclampsia-eclampsia and paternal age: A pilot study. Ginecologia y Obstetricia de Mexico, 190-196.
García-Ortiz, Liliana ; Gutiérrez-Salinas, José ; Galaviz-Hernández, Carlos ; Chima-Galán, María del Carmen ; Hilton-Cáceres, José M. ; Escobedo-Aguirre, Fernando ; de la Peña-Gutiérrez, Marlene ; Iniesta-Mejía, Antonio ; Miranda-Murillo, Juan. / Possible association between preeclampsia-eclampsia and paternal age: A pilot study. In: Ginecologia y Obstetricia de Mexico. 2011 ; pp. 190-196.
@article{4403d0a361724cfc8385d6f7a33f02b8,
title = "Possible association between preeclampsia-eclampsia and paternal age: A pilot study",
abstract = "Background: The preeclampsia is a multisystemic syndrome that occupied the first cause of maternal and fetal mortality around the world. Epidemiologic studies shown both mother and father contribute at the same risk for preeclampsia. Objective: To determinate if there is an association between preeclampsia and paternal age. Material and method: Preeclampsia-eclampsia patients and couples were analyzed in agree to {"}National High Blood Pressure Education Program Working Group{"} classification, and a control group constituted by normal pregnant women and couples was included. Results: There were 27 cases with mild preeclampsia and her couples, 13 cases with severe preeclampsia and her couples and 40 controls conformed by normal pregnant women and her couples. The statistical analysis of variance of the ages shown that men from preeclamptic group had a greater variance in contrast with man of control group (p < 0.001; valor of F = 5.084). Conclusions: Although is not clear how paternal age interview in preeclampsia risk, the interaction between paternal-maternal imprinting and spermatic senescence, followed by shortened telomeres of chromosome, could be produce the inactivity of a whole network of signals implicated in disease aetiology.",
author = "Liliana Garc{\'i}a-Ortiz and Jos{\'e} Guti{\'e}rrez-Salinas and Carlos Galaviz-Hern{\'a}ndez and Chima-Gal{\'a}n, {Mar{\'i}a del Carmen} and Hilton-C{\'a}ceres, {Jos{\'e} M.} and Fernando Escobedo-Aguirre and {de la Pe{\~n}a-Guti{\'e}rrez}, Marlene and Antonio Iniesta-Mej{\'i}a and Juan Miranda-Murillo",
year = "2011",
month = "1",
day = "1",
language = "American English",
pages = "190--196",
journal = "Ginecologia y Obstetricia de Mexico",
issn = "0300-9041",
publisher = "Asociacion Mexicana de Ginecologia y Obstetricia",

}

García-Ortiz, L, Gutiérrez-Salinas, J, Galaviz-Hernández, C, Chima-Galán, MDC, Hilton-Cáceres, JM, Escobedo-Aguirre, F, de la Peña-Gutiérrez, M, Iniesta-Mejía, A & Miranda-Murillo, J 2011, 'Possible association between preeclampsia-eclampsia and paternal age: A pilot study', Ginecologia y Obstetricia de Mexico, pp. 190-196.

Possible association between preeclampsia-eclampsia and paternal age: A pilot study. / García-Ortiz, Liliana; Gutiérrez-Salinas, José; Galaviz-Hernández, Carlos; Chima-Galán, María del Carmen; Hilton-Cáceres, José M.; Escobedo-Aguirre, Fernando; de la Peña-Gutiérrez, Marlene; Iniesta-Mejía, Antonio; Miranda-Murillo, Juan.

In: Ginecologia y Obstetricia de Mexico, 01.01.2011, p. 190-196.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Possible association between preeclampsia-eclampsia and paternal age: A pilot study

AU - García-Ortiz, Liliana

AU - Gutiérrez-Salinas, José

AU - Galaviz-Hernández, Carlos

AU - Chima-Galán, María del Carmen

AU - Hilton-Cáceres, José M.

AU - Escobedo-Aguirre, Fernando

AU - de la Peña-Gutiérrez, Marlene

AU - Iniesta-Mejía, Antonio

AU - Miranda-Murillo, Juan

PY - 2011/1/1

Y1 - 2011/1/1

N2 - Background: The preeclampsia is a multisystemic syndrome that occupied the first cause of maternal and fetal mortality around the world. Epidemiologic studies shown both mother and father contribute at the same risk for preeclampsia. Objective: To determinate if there is an association between preeclampsia and paternal age. Material and method: Preeclampsia-eclampsia patients and couples were analyzed in agree to "National High Blood Pressure Education Program Working Group" classification, and a control group constituted by normal pregnant women and couples was included. Results: There were 27 cases with mild preeclampsia and her couples, 13 cases with severe preeclampsia and her couples and 40 controls conformed by normal pregnant women and her couples. The statistical analysis of variance of the ages shown that men from preeclamptic group had a greater variance in contrast with man of control group (p < 0.001; valor of F = 5.084). Conclusions: Although is not clear how paternal age interview in preeclampsia risk, the interaction between paternal-maternal imprinting and spermatic senescence, followed by shortened telomeres of chromosome, could be produce the inactivity of a whole network of signals implicated in disease aetiology.

AB - Background: The preeclampsia is a multisystemic syndrome that occupied the first cause of maternal and fetal mortality around the world. Epidemiologic studies shown both mother and father contribute at the same risk for preeclampsia. Objective: To determinate if there is an association between preeclampsia and paternal age. Material and method: Preeclampsia-eclampsia patients and couples were analyzed in agree to "National High Blood Pressure Education Program Working Group" classification, and a control group constituted by normal pregnant women and couples was included. Results: There were 27 cases with mild preeclampsia and her couples, 13 cases with severe preeclampsia and her couples and 40 controls conformed by normal pregnant women and her couples. The statistical analysis of variance of the ages shown that men from preeclamptic group had a greater variance in contrast with man of control group (p < 0.001; valor of F = 5.084). Conclusions: Although is not clear how paternal age interview in preeclampsia risk, the interaction between paternal-maternal imprinting and spermatic senescence, followed by shortened telomeres of chromosome, could be produce the inactivity of a whole network of signals implicated in disease aetiology.

UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=79957555863&origin=inward

UR - https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=79957555863&origin=inward

M3 - Article

SP - 190

EP - 196

JO - Ginecologia y Obstetricia de Mexico

JF - Ginecologia y Obstetricia de Mexico

SN - 0300-9041

ER -

García-Ortiz L, Gutiérrez-Salinas J, Galaviz-Hernández C, Chima-Galán MDC, Hilton-Cáceres JM, Escobedo-Aguirre F et al. Possible association between preeclampsia-eclampsia and paternal age: A pilot study. Ginecologia y Obstetricia de Mexico. 2011 Jan 1;190-196.