Phycobiliproteins from Spirulina maxima and Pseudanabaena tenuis protect against hepatic damage and oxidative stress caused by Hg2+

Carlos Ángel Gallardo C, Edgar Cano E, Gabriel Eduardo López G, Vanessa Blas V, Roxana Olvera R, Margarita Franco C, Rocío Ortiz Butrón

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Abstract

The aim of this work was to evaluate if phycobiliproteins of P. tenuis y S. maxima protect from the hepatic damage and oxidative stress caused by Hg 2+. There were used 42 adult male mice, divided in: 1) control; 2) buffer phosphates (BP) + 5 mg/Kg of HgCl2 (ip); 3) BP + protean extract (PE) with 100 mg/kg of Spirulina maxima phycobiliproteins (ig); 4) BP + protean extract with 100 mg/kg of Pseudanabena tenuis phycobiliproteins (ig). The mice were sacrificed and the liver was obtained. LP, ROS, catalase and glutathione peroxidase were quantified, and histological analysis was made. It was found that phycobiliproteins from two cyanobacterias avoid the increase of LP and ROS, and they induced a rise of catalase that protects hepatic tissue damage caused by Hg2+.
Original languageAmerican English
Pages (from-to)30-35
Number of pages26
JournalRevista Mexicana de Ciencias Farmaceuticas
StatePublished - 1 Apr 2010

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Phycobiliproteins
Spirulina
catalase
phosphates
Oxidative Stress
buffers
damage
Buffers
mice
Liver
Phosphates
Catalase
glutathione
liver
Mercuric Chloride
Glutathione Peroxidase

Cite this

Gallardo C, Carlos Ángel ; Cano E, Edgar ; López G, Gabriel Eduardo ; Blas V, Vanessa ; Olvera R, Roxana ; Franco C, Margarita ; Ortiz Butrón, Rocío. / Phycobiliproteins from Spirulina maxima and Pseudanabaena tenuis protect against hepatic damage and oxidative stress caused by Hg2+. In: Revista Mexicana de Ciencias Farmaceuticas. 2010 ; pp. 30-35.
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abstract = "The aim of this work was to evaluate if phycobiliproteins of P. tenuis y S. maxima protect from the hepatic damage and oxidative stress caused by Hg 2+. There were used 42 adult male mice, divided in: 1) control; 2) buffer phosphates (BP) + 5 mg/Kg of HgCl2 (ip); 3) BP + protean extract (PE) with 100 mg/kg of Spirulina maxima phycobiliproteins (ig); 4) BP + protean extract with 100 mg/kg of Pseudanabena tenuis phycobiliproteins (ig). The mice were sacrificed and the liver was obtained. LP, ROS, catalase and glutathione peroxidase were quantified, and histological analysis was made. It was found that phycobiliproteins from two cyanobacterias avoid the increase of LP and ROS, and they induced a rise of catalase that protects hepatic tissue damage caused by Hg2+.",
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Phycobiliproteins from Spirulina maxima and Pseudanabaena tenuis protect against hepatic damage and oxidative stress caused by Hg2+. / Gallardo C, Carlos Ángel; Cano E, Edgar; López G, Gabriel Eduardo; Blas V, Vanessa; Olvera R, Roxana; Franco C, Margarita; Ortiz Butrón, Rocío.

In: Revista Mexicana de Ciencias Farmaceuticas, 01.04.2010, p. 30-35.

Research output: Contribution to journalArticleResearchpeer-review

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T1 - Phycobiliproteins from Spirulina maxima and Pseudanabaena tenuis protect against hepatic damage and oxidative stress caused by Hg2+

AU - Gallardo C, Carlos Ángel

AU - Cano E, Edgar

AU - López G, Gabriel Eduardo

AU - Blas V, Vanessa

AU - Olvera R, Roxana

AU - Franco C, Margarita

AU - Ortiz Butrón, Rocío

PY - 2010/4/1

Y1 - 2010/4/1

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AB - The aim of this work was to evaluate if phycobiliproteins of P. tenuis y S. maxima protect from the hepatic damage and oxidative stress caused by Hg 2+. There were used 42 adult male mice, divided in: 1) control; 2) buffer phosphates (BP) + 5 mg/Kg of HgCl2 (ip); 3) BP + protean extract (PE) with 100 mg/kg of Spirulina maxima phycobiliproteins (ig); 4) BP + protean extract with 100 mg/kg of Pseudanabena tenuis phycobiliproteins (ig). The mice were sacrificed and the liver was obtained. LP, ROS, catalase and glutathione peroxidase were quantified, and histological analysis was made. It was found that phycobiliproteins from two cyanobacterias avoid the increase of LP and ROS, and they induced a rise of catalase that protects hepatic tissue damage caused by Hg2+.

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