Phenylboronic acid/CuSO4 as an efficient catalyst for the synthesis of 1,4-disubstituted-1,2,3-triazoles from terminal acetylenes and alkyl azides

José Emilio De La Cerda-Pedro; Susana Rojas-Lima; Rosa Santillan; Heraclio López-Ruiz

Phenylboronic acid/CuSO₄ as an efficient catalyst for the synthesis of 1,4-disubstituted-1,2,3-triazoles from terminal acetylenes and alkyl azides

José Emilio De La Cerda-Pedro, Susana Rojas-Lima, Rosa Santillan, Heraclio López-Ruiz

Research output: Contribution to journal › Article › peer-review

Abstract

The synthesis of 1,4-disubstituted-1,2,3-triazoles from alkyl azides and terminal alkynes at room temperature and under microwave heating was attained using Cu(I), generated in-situ from copper(II) sulfate and phenylboronic acid, as catalyst. Twelve new triazoles were obtained in moderate to good yields (53-98%), and the products were obtained by crystallization from the mixture reaction without further purification.

Original language	English
Pages (from-to)	130-136
Number of pages	7
Journal	Journal of the Mexican Chemical Society
Volume	59
Issue number	2
State	Published - 1 Apr 2015
Externally published	Yes

Keywords

CuSO4
Microwave irradiation
Phenylboronic acid
Triazoles

Cite this

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title = "Phenylboronic acid/CuSO4 as an efficient catalyst for the synthesis of 1,4-disubstituted-1,2,3-triazoles from terminal acetylenes and alkyl azides",

abstract = "The synthesis of 1,4-disubstituted-1,2,3-triazoles from alkyl azides and terminal alkynes at room temperature and under microwave heating was attained using Cu(I), generated in-situ from copper(II) sulfate and phenylboronic acid, as catalyst. Twelve new triazoles were obtained in moderate to good yields (53-98%), and the products were obtained by crystallization from the mixture reaction without further purification.",

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author = "{De La Cerda-Pedro}, {Jos{\'e} Emilio} and Susana Rojas-Lima and Rosa Santillan and Heraclio L{\'o}pez-Ruiz",

note = "Publisher Copyright: {\textcopyright} 2015, Sociedad Qu{\'i}mica de M{\'e}xico.",

year = "2015",

month = apr,

day = "1",

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volume = "59",

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Phenylboronic acid/CuSO₄ as an efficient catalyst for the synthesis of 1,4-disubstituted-1,2,3-triazoles from terminal acetylenes and alkyl azides. / De La Cerda-Pedro, José Emilio; Rojas-Lima, Susana; Santillan, Rosa et al.
In: Journal of the Mexican Chemical Society, Vol. 59, No. 2, 01.04.2015, p. 130-136.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Phenylboronic acid/CuSO4 as an efficient catalyst for the synthesis of 1,4-disubstituted-1,2,3-triazoles from terminal acetylenes and alkyl azides

AU - De La Cerda-Pedro, José Emilio

AU - Rojas-Lima, Susana

AU - Santillan, Rosa

AU - López-Ruiz, Heraclio

PY - 2015/4/1

Y1 - 2015/4/1

N2 - The synthesis of 1,4-disubstituted-1,2,3-triazoles from alkyl azides and terminal alkynes at room temperature and under microwave heating was attained using Cu(I), generated in-situ from copper(II) sulfate and phenylboronic acid, as catalyst. Twelve new triazoles were obtained in moderate to good yields (53-98%), and the products were obtained by crystallization from the mixture reaction without further purification.

AB - The synthesis of 1,4-disubstituted-1,2,3-triazoles from alkyl azides and terminal alkynes at room temperature and under microwave heating was attained using Cu(I), generated in-situ from copper(II) sulfate and phenylboronic acid, as catalyst. Twelve new triazoles were obtained in moderate to good yields (53-98%), and the products were obtained by crystallization from the mixture reaction without further purification.

KW - CuSO4

KW - Microwave irradiation

KW - Phenylboronic acid

KW - Triazoles

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M3 - Artículo

SN - 1870-249X

VL - 59

SP - 130

EP - 136

JO - Journal of the Mexican Chemical Society

JF - Journal of the Mexican Chemical Society

IS - 2

ER -

Phenylboronic acid/CuSO₄ as an efficient catalyst for the synthesis of 1,4-disubstituted-1,2,3-triazoles from terminal acetylenes and alkyl azides

Abstract

Keywords

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