TY - JOUR
T1 - PHENOLICS CONTENT, ANTIOXIDANT POTENTIAL, α-GLUCOSIDASE AND α-AMYLASE INHIBITORY ACTIVITIES OF FOUR FOLIAR EXTRACTS FROM PINUS SPECIES
AU - Delgado-Alvarado, Eli Amanda
AU - Almaraz-Abarca, Norma
AU - Herrera-Arrieta, Yolanda
AU - Torres-Ricario, Rene
AU - González-Valdez, Laura Silvia
AU - Ávila-Reyes, José Antonio
AU - Naranjo-Jiménez, Néstor
N1 - Publisher Copyright:
© 2022, Romanian Society for Pharmaceutical Sciences. All rights reserved.
PY - 2022
Y1 - 2022
N2 - The current study focused on determining the contents of total phenolics (TP), flavonoids (FC), condensed tannins (CT), the flavonoid profiles, antioxidant potentials and α-glucosidase and α-amylase inhibitory capacities of the foliar extracts of Pinus engelmannii Carr., Pinus arizonica Engelm., Pinus durangensis Martínez and Pinus cembroides Zucc. Specific variations were found in TP, FC, CT, antioxidant potentials and α-glucosidase and α-amylase inhibitory activities. Pinus durangensis highlighted for its high level of FC (3.70 mg/g dry extract), high DPPH● scavenging activity, high ABTS●+ reducing potential, as well as its high inhibitory activity of α-glucosidase and α-amylase, whereas Pinus engelmannii for its high values of TP (340.15 mg/g dry extract) and CT (72.49 mg/g dry extract). Particularly, Pinus durangensis could support the development of hypoglycaemic treatments. The flavonoid profiles obtained by HPLC were species-specific, thus may be used for the development of chemical fingerprinting and quality control tools for the botanical authenticity of the bioactive extracts of these species of Pinus.
AB - The current study focused on determining the contents of total phenolics (TP), flavonoids (FC), condensed tannins (CT), the flavonoid profiles, antioxidant potentials and α-glucosidase and α-amylase inhibitory capacities of the foliar extracts of Pinus engelmannii Carr., Pinus arizonica Engelm., Pinus durangensis Martínez and Pinus cembroides Zucc. Specific variations were found in TP, FC, CT, antioxidant potentials and α-glucosidase and α-amylase inhibitory activities. Pinus durangensis highlighted for its high level of FC (3.70 mg/g dry extract), high DPPH● scavenging activity, high ABTS●+ reducing potential, as well as its high inhibitory activity of α-glucosidase and α-amylase, whereas Pinus engelmannii for its high values of TP (340.15 mg/g dry extract) and CT (72.49 mg/g dry extract). Particularly, Pinus durangensis could support the development of hypoglycaemic treatments. The flavonoid profiles obtained by HPLC were species-specific, thus may be used for the development of chemical fingerprinting and quality control tools for the botanical authenticity of the bioactive extracts of these species of Pinus.
KW - Pinus
KW - antioxidants
KW - flavonoid profiles
KW - hypoglycaemic
UR - http://www.scopus.com/inward/record.url?scp=85129724199&partnerID=8YFLogxK
U2 - 10.31925/farmacia.2022.2.5
DO - 10.31925/farmacia.2022.2.5
M3 - Artículo
AN - SCOPUS:85129724199
SN - 0014-8237
VL - 70
SP - 214
EP - 221
JO - Farmacia
JF - Farmacia
IS - 2
ER -