Pharmacokinetic principles in the use of antibiotics in pediatrics

María Gabriela Pérez Guille, Ismael Lares-Asseff, Alejandra Toledo López

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

One of the challenges in the field of pediatric infectology is how to make a potent antibiotic drug to arrive at the site of infection in active form and inadequate concentration throughout the time required for the drug to exercise its action. In addition, the antibiotic must not interfere with the host's natural defense mechanism, such as phagocytosis and must be cleared from the body once it has completed its task, since its long-term permanence increases the risk of toxicity. In this chapter, the experience of three clinical cases is presented.

Original languageEnglish
Title of host publicationThe Optimization of Drug Prescribing in Children
PublisherNova Science Publishers, Inc.
Pages113-132
Number of pages20
ISBN (Electronic)9781536130263
ISBN (Print)9781536122633
StatePublished - 1 Jan 2018

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