Pharmacokinetic, growth and development

Ismael Lares-Asseff, Gabriela Pérez Guille

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

© 2018 by Nova Science Publishers, Inc. All rights reserved. During the different stages of life, processes of immaturity, maturity and aging occur, where the body undergoes different changes such as anatomical, physical and biochemical, these processes alter the pharmacokinetics of drugs, together with the individual comorbidities and nutritional status of each patient. It is therefore important to know the pharmacokinetics to individualize medical therapeutics. A fundamental aspect of medicine is medical therapeutics. Unfortunately, only the body weight is considered to administer the dose of a drug, hoping that the therapeutic response is good and similar in different groups of patients, without considering the homeostatic vision of the organism and biological variability. Pharmacological success is evaluated through the empirical test and error criterion, therefore the pharmacological dose is increased or decreased according to the response. It is not generally questioned whether the therapeutic dose is adequate to achieve and maintain plasma levels within the therapeutic range, which is very important to ensure the pharmacological goal. The application of the principles of pharmacokinetics in therapeutic management is important to predict distribution and elimination of drugs in the body through knowledge of plasma concentration curves. The purpose of this chapter is to sensitize the physician and health professionals, to give a better pharmacological management in children.
Original languageAmerican English
Title of host publicationThe Optimization of Drug Prescribing in Children
Number of pages26
ISBN (Electronic)9781536130263
StatePublished - 1 Jan 2018

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Growth and Development
Pharmacokinetics
Pharmacology
Biochemical Phenomena
Therapeutics
Pharmaceutical Preparations
Physical Phenomena
Nutritional Status
Comorbidity
Body Weight
Medicine
Physicians
Health

Cite this

Lares-Asseff, I., & Guille, G. P. (2018). Pharmacokinetic, growth and development. In The Optimization of Drug Prescribing in Children
Lares-Asseff, Ismael ; Guille, Gabriela Pérez. / Pharmacokinetic, growth and development. The Optimization of Drug Prescribing in Children. 2018.
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Lares-Asseff, I & Guille, GP 2018, Pharmacokinetic, growth and development. in The Optimization of Drug Prescribing in Children.

Pharmacokinetic, growth and development. / Lares-Asseff, Ismael; Guille, Gabriela Pérez.

The Optimization of Drug Prescribing in Children. 2018.

Research output: Chapter in Book/Report/Conference proceedingChapter

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Lares-Asseff I, Guille GP. Pharmacokinetic, growth and development. In The Optimization of Drug Prescribing in Children. 2018