Organic biocides hosted in layered double hydroxides: Enhancing antimicrobial activity: Hybrid organic-inorganic biocides

Alejandra Santana Cruz, Jorge Flores, Roberto Guerra, Carlos Felipe, Enrique Lima

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Samples of layered double hydroxides containing carbonates as compensating anions were prepared by the urea method. These LDHs were used as hosts of anions coming from pipemidic and nalidixic acid. XRD results confirm that these anions were hosted in the interlayer space of LDHs. Further, from 27Al NMR MAS characterization of an interaction between the brucite-like layers and anions was suggested. Then the hybrids LDHs were used as biocide of Salmonella typhi and Escherichia coli. The release profile of pipemidic and nalidixic anions from hybrid LDHs occurs for periods as long as 3.5 hours. The free-organic acid LDHs were not able to kill S. Typhi, neither E. coli. In contrast, the hybrids LDHs eliminate almost completely bacteria within short times.

Original languageEnglish
Pages (from-to)163-169
Number of pages7
JournalOpen Chemistry
Volume16
Issue number1
DOIs
StatePublished - 9 Mar 2018

Keywords

  • Adsorption
  • Biocides
  • Escherichia coli
  • Layered Double Hydroxides
  • Salmonella typhi

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