Optical methods and image processing as a quantitative tool in photodynamic therapy: A proof of concept

Josue D. Rivera-Fernandez, Karen Roa-Tort, Jose M. De La Rosa-Vazquez, Alma Valor-Reed, Suren Stolik-Isakina, Diego A. Fabila-Bustos, Carolina Guzman-Arriaga, Galileo Escobedo

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Scopus citations

Abstract

This paper presents the first results of the combination of optical techniques, through fluorescence images captured by endoscopic techniques, and imaging processing methods to give a quantitative result that will be useful to physicians to observing and following up Photodynamic Therapy (PDT) for liver cancer. The experiment was applied to an animal model using δ-aminolevulinic acid (ALA) as a photosensitizing agent, red light for the application of PDT, white light for diffuse reflectance and light of 405 nm for the capture of fluorescence photographs with endoscopic procedures on the surface of the liver. As part of the image processing, metrics such as the Euclidean distance were used and the RGB color composition components.

Original languageEnglish
Title of host publicationCONIELECOMP 2019 - 2019 International Conference on Electronics, Communications and Computers
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9781728111452
DOIs
StatePublished - 22 Mar 2019
Event2019 International Conference on Electronics, Communications and Computers, CONIELECOMP 2019 - Cholula, Mexico
Duration: 27 Feb 20191 Mar 2019

Publication series

NameCONIELECOMP 2019 - 2019 International Conference on Electronics, Communications and Computers

Conference

Conference2019 International Conference on Electronics, Communications and Computers, CONIELECOMP 2019
Country/TerritoryMexico
CityCholula
Period27/02/191/03/19

Keywords

  • Photodynamic Therapy
  • endoscopy images
  • fluorescence
  • imaging processing
  • liver tissue
  • δ-aminolevulinic acid

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