Microwave-assisted C-3 selective oxidative radical alkylation of flavones

Marco V. Mijangos, Joaquin González-Marrero, Luis D. Miranda, Paulette Vincent-Ruz, Armando Lujan-Montelongo, Diana Olivera-Díaz, Elhiu Bautista, Alfredo Ortega, María De La Luz Campos-González, Rocio Gamez-Montaño

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

Flavones were directly alkylated at the C-3 position in moderate yields using a xanthate-based oxidative radical addition procedure. This methodology is a suitable synthetic tool for the direct substitution of the vinylic and unactivated C-H bond of the C ring of the flavone by an alkyl functionality under neutral conditions.

Original languageEnglish
Pages (from-to)2946-2949
Number of pages4
JournalOrganic and Biomolecular Chemistry
Volume10
Issue number15
DOIs
StatePublished - 21 Apr 2012

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