Metals and nonsteroidal anti-inflammatory pharmaceuticals drugs present in water from Madín Reservoir (Mexico) induce oxidative stress in gill, blood, and muscle of common carp (Cyprinus carpio)

Edgar David González-González, Leobardo Manuel Gómez-Oliván, Marcela Galar-Martínez, Patricia Vieyra-Reyes, Hariz Islas-Flores, Sandra García-Medina, Juan Manuel Jiménez-Vargas, Celene Razo-Estrada, Ricardo Pérez-Pastén

Research output: Contribution to journalArticlepeer-review

35 Scopus citations

Abstract

Many toxic xenobiotics that enter the aquatic environment exert their effects through redox cycling. Oxidative stress, which incorporates both oxidative damage and antioxidant defenses, is a common effect induced in organisms exposed to xenobiotics in their environment. The results of the present study aimed to determine the oxidative stress induced in the common carp Cyprinus carpio by contaminants [metals and nonsteroidal anti-inflammatory drugs (NSAIDs)] present in Madín Reservoir. Five sampling stations (SSs), considered to have the most problems due to discharges, were selected. Carp were exposed to water from each SS for 96 h, and the following biomarkers were evaluated in gill, blood, and muscle: hydroperoxide content, lipid peroxidation, protein carbonyl content, and the activity of antioxidant enzymes superoxide dismutase and catalase. Results show that contaminants (metals and NSAIDs) present in water from the different SSs induce oxidative stress. Thus, water in this reservoir is contaminated with xenobiotics that are hazardous to C. carpio, a species consumed by the local human population.

Original languageEnglish
Pages (from-to)281-295
Number of pages15
JournalArchives of Environmental Contamination and Toxicology
Volume67
Issue number2
DOIs
StatePublished - Aug 2014

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