Irradiation system for interstitial photodynamic therapy

L. Pacheco, S. Stolik, J. De La Rosa

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Interstitial Photodynamic Therapy (IPDT) is a promising form of treatment of deep-seated and bulky malignant tumors, based on the lethal cell response to the photochemical reactions when drug is light activated in presence of oxygen. In order to accomplish an effective internal illumination, laser sources are preferably used because of two important reasons: the monochromatic light can be confined to the narrow absorption band of the drug and the laser beam is easily focused into optical fibers. In this work the development of a diode-laser-light-source is presented. The system is tuned by temperature to get a better match in the 5-ALA absorption band. This system also comprises a trifurcated fiber system to accomplish interstitial illumination.

Original languageEnglish
Title of host publication8th Iberoamerican Optics Meeting and 11th Latin American Meeting on Optics, Lasers, and Applications
DOIs
StatePublished - 2013
Event8th Iberoamerican Optics Meeting, RIAO 2013 and 11th Latin American Meeting on Optics, Lasers, and Applications, OPTILAS 2013 - Porto, Portugal
Duration: 22 Jul 201326 Jul 2013

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume8785
ISSN (Print)0277-786X
ISSN (Electronic)1996-756X

Conference

Conference8th Iberoamerican Optics Meeting, RIAO 2013 and 11th Latin American Meeting on Optics, Lasers, and Applications, OPTILAS 2013
Country/TerritoryPortugal
CityPorto
Period22/07/1326/07/13

Keywords

  • 5-Aminolevulinic acid
  • Laser diode
  • Photodynamic Therapy (IPDT)

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