Innovative biosensor of circulating breast cancer cells; a potential tool in latin america oncology rooms

César A. González, Herberth Bravo

Research output: Contribution to conferencePaperResearch

Abstract

© Springer Nature Singapore Pte Ltd. 2019. The detection of circulating tumoral cells represents the possibility for therapy monitoring as well as prevent metastasis in oncology patients. Portable and economical technologies are required in most of the oncology rooms of third level Latin America hospitals. In this work an innovative biosensor of circulating breast cancer cells on the basis of bioimpedance spectroscopy measurements assisted with magnetic nanoparticles is presented. The technical proposal involves a microfluidic system for cancer cells separation by immunomagnetic technique and its detection by multifrequency bioimpedance measurements. An experimental proof of concept to detect a typical breast cancer cell line was developed to evaluate the sensitivity of the system. The results shown the technical proposal feasibility as portable, inexpensive and non-invasive biosensor of circulating tumoral cells, as well as its technical feasibility for implementation in oncology rooms of Latin America third level hospitals.
Original languageAmerican English
Pages765-768
Number of pages688
DOIs
StatePublished - 1 Jan 2019
EventIFMBE Proceedings -
Duration: 1 Jan 2019 → …

Conference

ConferenceIFMBE Proceedings
Period1/01/19 → …

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Latin America
Biosensing Techniques
Breast Neoplasms
Immunomagnetic Separation
Microfluidics
Singapore
Nanoparticles
Spectrum Analysis
Neoplasm Metastasis
Technology
Cell Line
Neoplasms
Therapeutics

Cite this

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Innovative biosensor of circulating breast cancer cells; a potential tool in latin america oncology rooms. / González, César A.; Bravo, Herberth.

2019. 765-768 Paper presented at IFMBE Proceedings, .

Research output: Contribution to conferencePaperResearch

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