Influence of the State of the Subarachnoid Space of the Cranial Base in Hydrocephalus Resolution after Endoscopy

Jose Juan Sanchez Rodriguez, Jaime Torres-Corzo, Dominic Shelby Cervantes, Roberto Rodriguez-DellaVecchia, Antonio Gordillo-Moscoso, Juan Manuel Vinas-Rios, Martin Sanchez-Aguilar

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Objective To compare the resolution rate of hydrocephalus after endoscopy (predominantly endoscopic third ventriculostomy [ETV]) using flexible endoscopes during a 5-year period in patients with a permeable and a nonpermeable subarachnoid space (SAS). Material and Methods We conducted a retrospective cohort study of the videos and records of 150 hydrocephalic patients chosen randomly who underwent ETV (and other endoscopic procedures) with a flexible endoscope. The patients were classified into two groups based on the neuroendoscopic findings. The first group included patients with a permeable SAS, and the second group included patients with a nonpermeable SAS. A normal SAS or one with slight arachnoiditis was considered permeable. Adhesive arachnoiditis and immature or mechanically obliterated SASs were considered nonpermeable. Results We found a success rate of 70% in patients with a permeable SAS versus 33% in patients with a nonpermeable SAS. The baseline characteristics of both groups were homogeneous. We obtained a statistically significant difference (p < 0.0001) with hazard ratio (HR) 3.42 (95% confidence interval [CI], 1.88-6.22). Another important factor involved was age that showed a statistically significant difference (p < 0.0018) with HR 3.28 (95% CI, 1.55-6.93). Conclusion The permeability of the SAS is an important prognostic factor in the resolution rate of hydrocephalus after ETV (and other endoscopic procedures) using flexible neuroendoscopes. Therefore we recommend that the characteristics of the SAS be examined following every endoscopic procedure for hydrocephalus to identify patients at risk of recurrence.

Original languageEnglish
Article number151526oa
Pages (from-to)255-259
Number of pages5
JournalJournal of Neurological Surgery, Part A: Central European Neurosurgery
Volume78
Issue number3
DOIs
StatePublished - 1 May 2017
Externally publishedYes

Keywords

  • flexible neuroendoscopy
  • hydrocephalus
  • subarachnoid space
  • third ventriculoscopy

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