In vitro antifungal activity of coumarin extracted from Loeselia mexicana Brand

Victor M. Navarro-García; Gabriela Rojas; Margarita Avilés; Macrina Fuentes; Gerardo Zepeda

doi:10.1111/j.1439-0507.2010.01993.x

In vitro antifungal activity of coumarin extracted from Loeselia mexicana Brand

Victor M. Navarro-García, Gabriela Rojas, Margarita Avilés, Macrina Fuentes, Gerardo Zepeda

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Abstract

The bis-coumarin daphnoretin and its monomeric precursors scopoletin and umbelliferone were isolated for the first time from the aerial part of Loeselia mexicana Brand (a vegetal species used in Mexican traditional medicine) using chromatographic techniques. The structures of these compounds were determined by ¹H and ¹³C NMR analyses. These coumarins were evaluated for in vitro antifungal activity. The three compounds tested showed significant antifungal activity.

Original language	English
Pages (from-to)	e569-e571
Journal	Mycoses
Volume	54
Issue number	5
DOIs	https://doi.org/10.1111/j.1439-0507.2010.01993.x
State	Published - Sep 2011
Externally published	Yes

Keywords

Antifungal activity
Coumarins
Dermatophytes
Folk medicine
Loeselia mexicana
Superficial infection

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10.1111/j.1439-0507.2010.01993.x

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title = "In vitro antifungal activity of coumarin extracted from Loeselia mexicana Brand",

abstract = "The bis-coumarin daphnoretin and its monomeric precursors scopoletin and umbelliferone were isolated for the first time from the aerial part of Loeselia mexicana Brand (a vegetal species used in Mexican traditional medicine) using chromatographic techniques. The structures of these compounds were determined by 1H and 13C NMR analyses. These coumarins were evaluated for in vitro antifungal activity. The three compounds tested showed significant antifungal activity.",

keywords = "Antifungal activity, Coumarins, Dermatophytes, Folk medicine, Loeselia mexicana, Superficial infection",

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AU - Navarro-García, Victor M.

AU - Rojas, Gabriela

AU - Avilés, Margarita

AU - Fuentes, Macrina

AU - Zepeda, Gerardo

PY - 2011/9

Y1 - 2011/9

N2 - The bis-coumarin daphnoretin and its monomeric precursors scopoletin and umbelliferone were isolated for the first time from the aerial part of Loeselia mexicana Brand (a vegetal species used in Mexican traditional medicine) using chromatographic techniques. The structures of these compounds were determined by 1H and 13C NMR analyses. These coumarins were evaluated for in vitro antifungal activity. The three compounds tested showed significant antifungal activity.

AB - The bis-coumarin daphnoretin and its monomeric precursors scopoletin and umbelliferone were isolated for the first time from the aerial part of Loeselia mexicana Brand (a vegetal species used in Mexican traditional medicine) using chromatographic techniques. The structures of these compounds were determined by 1H and 13C NMR analyses. These coumarins were evaluated for in vitro antifungal activity. The three compounds tested showed significant antifungal activity.

KW - Antifungal activity

KW - Coumarins

KW - Dermatophytes

KW - Folk medicine

KW - Loeselia mexicana

KW - Superficial infection

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DO - 10.1111/j.1439-0507.2010.01993.x

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VL - 54

SP - e569-e571

JO - Mycoses

JF - Mycoses

IS - 5

ER -

In vitro antifungal activity of coumarin extracted from Loeselia mexicana Brand

Abstract

Keywords

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