Improving immunogenicity of poultry vaccines by use of molecular adjuvants

Alvaro R. Escalante-Sansores, Angel E. Absalón, Diana V. Cortés-Espinosa

Research output: Contribution to journalReview articlepeer-review

Abstract

SUMMARY: Currently, vaccination is still the main strategy to prevent important pathologies in the poultry industry. Furthermore, with the growing trend to develop vectorized or nucleic acid vaccines, new obstacles have emerged, for instance, the low immunogenicity this type of vaccine generates. As a consequence, the search for new, safe, and effective adjuvants has taken on greater importance. With the recent advances in avian immunology and genetics, new alternatives to traditional adjuvants have emerged, such as the use of immunomodulatory proteins with the potential to enhance the humoral and cellular immune response generated by vaccines. These recently developed types of adjuvants are named molecular adjuvants. This review summarizes the advances achieved so far using molecular adjuvants to prevent some of the critical diseases in the poultry industry.

Original languageEnglish
Pages (from-to)705-726
Number of pages22
JournalWorld's Poultry Science Journal
Volume78
Issue number3
DOIs
StatePublished - 2022

Keywords

  • Molecular adjuvant
  • chicken vaccine
  • cytokines
  • immune system

Fingerprint

Dive into the research topics of 'Improving immunogenicity of poultry vaccines by use of molecular adjuvants'. Together they form a unique fingerprint.

Cite this