Hepatoprotector effect of Trametes versicolor mycelium in a mouse model strain NIH

Research output: Contribution to journalArticleResearchpeer-review

Abstract

© 2015, Asociacion Farmaceutica Mexicana A.C. All rights reserved. Currently, there has been increasing the interest in compounds contains in fungi, because they have health bene_ts. Therefore, it was determined whether ethanol, extract, and their fractions (ethyl acetate and hexane), obtains from mycelium of Trametes versicolor prevents oxidative stress and tissue damage-caused by CCl4intoxication. The ethanol extract and sub-fractions were administered to NIH male mice. Subsequently, the liver was obtained for quantifying oxidative stress, redox environment, and histological damage. We found that extracts decreased oxidative stress, and they prevent cellular damage-caused by CCl4. It is concluded that ethanol extract and its fractions (ethyl acetate and hexane) protect against acute liver damage.
Original languageAmerican English
Pages (from-to)56-63
Number of pages49
JournalRevista Mexicana de Ciencias Farmaceuticas
StatePublished - 1 Jan 2015

Fingerprint

Trametes
Oxidative stress
Mycelium
Oxidative Stress
Ethanol
Hexanes
Hexane
Liver
Fungi
Oxidation-Reduction
Health
Tissue
ethyl acetate

Cite this

@article{eaf99b5e1831418db0967d599bff920b,
title = "Hepatoprotector effect of Trametes versicolor mycelium in a mouse model strain NIH",
abstract = "{\circledC} 2015, Asociacion Farmaceutica Mexicana A.C. All rights reserved. Currently, there has been increasing the interest in compounds contains in fungi, because they have health bene_ts. Therefore, it was determined whether ethanol, extract, and their fractions (ethyl acetate and hexane), obtains from mycelium of Trametes versicolor prevents oxidative stress and tissue damage-caused by CCl4intoxication. The ethanol extract and sub-fractions were administered to NIH male mice. Subsequently, the liver was obtained for quantifying oxidative stress, redox environment, and histological damage. We found that extracts decreased oxidative stress, and they prevent cellular damage-caused by CCl4. It is concluded that ethanol extract and its fractions (ethyl acetate and hexane) protect against acute liver damage.",
author = "Placido Rojas-Franco and Edgar Cano-Europa and Rocio Ortiz-Butron and Ricardo Valenzuela-Garza and Vanessa Blas-Valdivia and Margarita Franco-Colin",
year = "2015",
month = "1",
day = "1",
language = "American English",
pages = "56--63",
journal = "Revista Mexicana de Ciencias Farmaceuticas",
issn = "1027-3956",
publisher = "Asociacion Farmaceutica Mexicana A.C.",

}

TY - JOUR

T1 - Hepatoprotector effect of Trametes versicolor mycelium in a mouse model strain NIH

AU - Rojas-Franco, Placido

AU - Cano-Europa, Edgar

AU - Ortiz-Butron, Rocio

AU - Valenzuela-Garza, Ricardo

AU - Blas-Valdivia, Vanessa

AU - Franco-Colin, Margarita

PY - 2015/1/1

Y1 - 2015/1/1

N2 - © 2015, Asociacion Farmaceutica Mexicana A.C. All rights reserved. Currently, there has been increasing the interest in compounds contains in fungi, because they have health bene_ts. Therefore, it was determined whether ethanol, extract, and their fractions (ethyl acetate and hexane), obtains from mycelium of Trametes versicolor prevents oxidative stress and tissue damage-caused by CCl4intoxication. The ethanol extract and sub-fractions were administered to NIH male mice. Subsequently, the liver was obtained for quantifying oxidative stress, redox environment, and histological damage. We found that extracts decreased oxidative stress, and they prevent cellular damage-caused by CCl4. It is concluded that ethanol extract and its fractions (ethyl acetate and hexane) protect against acute liver damage.

AB - © 2015, Asociacion Farmaceutica Mexicana A.C. All rights reserved. Currently, there has been increasing the interest in compounds contains in fungi, because they have health bene_ts. Therefore, it was determined whether ethanol, extract, and their fractions (ethyl acetate and hexane), obtains from mycelium of Trametes versicolor prevents oxidative stress and tissue damage-caused by CCl4intoxication. The ethanol extract and sub-fractions were administered to NIH male mice. Subsequently, the liver was obtained for quantifying oxidative stress, redox environment, and histological damage. We found that extracts decreased oxidative stress, and they prevent cellular damage-caused by CCl4. It is concluded that ethanol extract and its fractions (ethyl acetate and hexane) protect against acute liver damage.

UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84994651222&origin=inward

UR - https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=84994651222&origin=inward

M3 - Article

SP - 56

EP - 63

JO - Revista Mexicana de Ciencias Farmaceuticas

JF - Revista Mexicana de Ciencias Farmaceuticas

SN - 1027-3956

ER -