Efecto hepatoprotector del micelio de Trametes versicolor en un modelo de ratón de la cepa NIH

Placido Rojas-Franco; Edgar Cano-Europa; Rocio Ortiz-Butron; Ricardo Valenzuela-Garza; Vanessa Blas-Valdivia; Margarita Franco-Colin

Efecto hepatoprotector del micelio de Trametes versicolor en un modelo de ratón de la cepa NIH

Translated title of the contribution: Hepatoprotector effect of Trametes versicolor mycelium in a mouse model strain NIH

Placido Rojas-Franco, Edgar Cano-Europa, Rocio Ortiz-Butron, Ricardo Valenzuela-Garza, Vanessa Blas-Valdivia, Margarita Franco-Colin

Escuela Nacional de Ciencias Biológicas (ENCB)

Research output: Contribution to journal › Article › peer-review

Abstract

Currently, there has been increasing the interest in compounds contains in fungi, because they have health bene_ts. Therefore, it was determined whether ethanol, extract, and their fractions (ethyl acetate and hexane), obtains from mycelium of Trametes versicolor prevents oxidative stress and tissue damage-caused by CCl₄ intoxication. The ethanol extract and sub-fractions were administered to NIH male mice. Subsequently, the liver was obtained for quantifying oxidative stress, redox environment, and histological damage. We found that extracts decreased oxidative stress, and they prevent cellular damage-caused by CCl₄. It is concluded that ethanol extract and its fractions (ethyl acetate and hexane) protect against acute liver damage.

Translated title of the contribution	Hepatoprotector effect of Trametes versicolor mycelium in a mouse model strain NIH
Original language	Spanish
Pages (from-to)	56-63
Number of pages	8
Journal	Revista Mexicana de Ciencias Farmaceuticas
Volume	46
Issue number	1
State	Published - 1 Jan 2015

Cite this

@article{eaf99b5e1831418db0967d599bff920b,

title = "Efecto hepatoprotector del micelio de Trametes versicolor en un modelo de rat{\'o}n de la cepa NIH",

abstract = "Currently, there has been increasing the interest in compounds contains in fungi, because they have health bene_ts. Therefore, it was determined whether ethanol, extract, and their fractions (ethyl acetate and hexane), obtains from mycelium of Trametes versicolor prevents oxidative stress and tissue damage-caused by CCl4 intoxication. The ethanol extract and sub-fractions were administered to NIH male mice. Subsequently, the liver was obtained for quantifying oxidative stress, redox environment, and histological damage. We found that extracts decreased oxidative stress, and they prevent cellular damage-caused by CCl4. It is concluded that ethanol extract and its fractions (ethyl acetate and hexane) protect against acute liver damage.",

keywords = "CCl, Hepatic protection, Oxidative stress, Trametes versicolor",

author = "Placido Rojas-Franco and Edgar Cano-Europa and Rocio Ortiz-Butron and Ricardo Valenzuela-Garza and Vanessa Blas-Valdivia and Margarita Franco-Colin",

year = "2015",

month = jan,

day = "1",

language = "Espa{\~n}ol",

volume = "46",

pages = "56--63",

journal = "Revista Mexicana de Ciencias Farmaceuticas",

issn = "1027-3956",

number = "1",

}

TY - JOUR

T1 - Efecto hepatoprotector del micelio de Trametes versicolor en un modelo de ratón de la cepa NIH

AU - Rojas-Franco, Placido

AU - Cano-Europa, Edgar

AU - Ortiz-Butron, Rocio

AU - Valenzuela-Garza, Ricardo

AU - Blas-Valdivia, Vanessa

AU - Franco-Colin, Margarita

PY - 2015/1/1

Y1 - 2015/1/1

N2 - Currently, there has been increasing the interest in compounds contains in fungi, because they have health bene_ts. Therefore, it was determined whether ethanol, extract, and their fractions (ethyl acetate and hexane), obtains from mycelium of Trametes versicolor prevents oxidative stress and tissue damage-caused by CCl4 intoxication. The ethanol extract and sub-fractions were administered to NIH male mice. Subsequently, the liver was obtained for quantifying oxidative stress, redox environment, and histological damage. We found that extracts decreased oxidative stress, and they prevent cellular damage-caused by CCl4. It is concluded that ethanol extract and its fractions (ethyl acetate and hexane) protect against acute liver damage.

AB - Currently, there has been increasing the interest in compounds contains in fungi, because they have health bene_ts. Therefore, it was determined whether ethanol, extract, and their fractions (ethyl acetate and hexane), obtains from mycelium of Trametes versicolor prevents oxidative stress and tissue damage-caused by CCl4 intoxication. The ethanol extract and sub-fractions were administered to NIH male mice. Subsequently, the liver was obtained for quantifying oxidative stress, redox environment, and histological damage. We found that extracts decreased oxidative stress, and they prevent cellular damage-caused by CCl4. It is concluded that ethanol extract and its fractions (ethyl acetate and hexane) protect against acute liver damage.

KW - CCl

KW - Hepatic protection

KW - Oxidative stress

KW - Trametes versicolor

UR - http://www.scopus.com/inward/record.url?scp=84994651222&partnerID=8YFLogxK

M3 - Artículo

SN - 1027-3956

VL - 46

SP - 56

EP - 63

JO - Revista Mexicana de Ciencias Farmaceuticas

JF - Revista Mexicana de Ciencias Farmaceuticas

IS - 1

ER -

Efecto hepatoprotector del micelio de Trametes versicolor en un modelo de ratón de la cepa NIH

Abstract

Other files and links

Fingerprint

Cite this