TY - JOUR
T1 - Global longitudinal strain is superior to ejection fraction for detecting myocardial dysfunction in end-stage renal disease with hyperparathyroidism
AU - Carrasco-Ruiz, Maria Fernanda
AU - Ruiz-Rivera, Antonio
AU - Soriano-Ursúa, Marvin A.
AU - Martinez-Hernandez, Carlos
AU - Manuel-Apolinar, Leticia
AU - Castillo-Hernandez, Carmen
AU - Guevara-Balcazar, Gustavo
AU - Farfán-García, Eunice D.
AU - Mejia-Ruiz, Ana
AU - Rubio-Gayosso, Ivan
AU - Perez-Capistran, Teresa
N1 - Publisher Copyright:
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
PY - 2022/4/1
Y1 - 2022/4/1
N2 - BACKGROUND The estimation of left ventricular ejection fraction (LVEF) by 2D echocardiography (2D-ECHO) is the most used tool to assess LV systolic function (LVSF). Global longitudinal strain (GLS) has recently been suggested as a superior method for several evaluations. This study explored the association and prevalence of LV systolic dysfunction (LVSD) by using these methods in patients with end-stage renal disease (ESRD) and severe hyperparathyroidism (SHPTH); both associated with cardiovascular events (CEs). AIM To evaluate the myocardial function in patients with ESRD and SHPTH by using the GLS and LVEF measured through conventional 2D-ECHO. METHODS In 62 patients with ESRD and SHPTH, asymptomatic, and without a history of CEs, LVSF was evaluated by 2D-ECHO, obtaining the EF, by the Simpson biplane method, and GLS by speckle tracking. RESULTS The total patients with ESRD had a preserved LVEF (> 50%) but abnormal GLS (< 13.55%). Additionally, multivariate analysis showed an independent association of GLS and serum parathyroid hormone (PTH), LV mass index, and hemoglobin. Also, PTH was independently associated with lateral e' wave and tricuspid regurgitation velocity. CONCLUSION In patients with SHPTH linked to ESRD, the use of GLS by 2D-ECHO is a more sensitive tool than LVEF for detecting LVSD.
AB - BACKGROUND The estimation of left ventricular ejection fraction (LVEF) by 2D echocardiography (2D-ECHO) is the most used tool to assess LV systolic function (LVSF). Global longitudinal strain (GLS) has recently been suggested as a superior method for several evaluations. This study explored the association and prevalence of LV systolic dysfunction (LVSD) by using these methods in patients with end-stage renal disease (ESRD) and severe hyperparathyroidism (SHPTH); both associated with cardiovascular events (CEs). AIM To evaluate the myocardial function in patients with ESRD and SHPTH by using the GLS and LVEF measured through conventional 2D-ECHO. METHODS In 62 patients with ESRD and SHPTH, asymptomatic, and without a history of CEs, LVSF was evaluated by 2D-ECHO, obtaining the EF, by the Simpson biplane method, and GLS by speckle tracking. RESULTS The total patients with ESRD had a preserved LVEF (> 50%) but abnormal GLS (< 13.55%). Additionally, multivariate analysis showed an independent association of GLS and serum parathyroid hormone (PTH), LV mass index, and hemoglobin. Also, PTH was independently associated with lateral e' wave and tricuspid regurgitation velocity. CONCLUSION In patients with SHPTH linked to ESRD, the use of GLS by 2D-ECHO is a more sensitive tool than LVEF for detecting LVSD.
KW - End-stage renal disease
KW - Global longitudinal strain
KW - Left ventricular hypertrophy
KW - Parathormone
KW - Systolic dysfunction
UR - http://www.scopus.com/inward/record.url?scp=85129913527&partnerID=8YFLogxK
U2 - 10.4330/WJC.V14.I4.239
DO - 10.4330/WJC.V14.I4.239
M3 - Artículo
C2 - 35582470
AN - SCOPUS:85129913527
SN - 1949-8462
VL - 14
SP - 239
EP - 249
JO - World Journal of Cardiology
JF - World Journal of Cardiology
IS - 4
ER -