TY - JOUR
T1 - Experimental Determination of High-Order Bending Elastic Constants of Lipid Bilayers
AU - Toscano-Flores, Liliana G.
AU - Jacinto-Méndez, Damián
AU - Carbajal-Tinoco, Mauricio D.
N1 - Publisher Copyright:
© 2016 American Chemical Society.
PY - 2016/6/30
Y1 - 2016/6/30
N2 - We present a method to describe the formation of small lipid vesicles in terms of three bending elastic constants that can be experimentally measured. Our method combines a general expression of the elastic free energy of the bilayer and the thermodynamic description of molecular aggregation. The resulting model requires the size distribution of liposomes, which is determined from the X-ray scattered intensity spectra of vesicular dispersions. By using two different preparation methods, we studied a series of vesicular solutions made of distinct lipids and we obtained their corresponding bending elastic constants that are consistent with known bending rigidities.
AB - We present a method to describe the formation of small lipid vesicles in terms of three bending elastic constants that can be experimentally measured. Our method combines a general expression of the elastic free energy of the bilayer and the thermodynamic description of molecular aggregation. The resulting model requires the size distribution of liposomes, which is determined from the X-ray scattered intensity spectra of vesicular dispersions. By using two different preparation methods, we studied a series of vesicular solutions made of distinct lipids and we obtained their corresponding bending elastic constants that are consistent with known bending rigidities.
UR - http://www.scopus.com/inward/record.url?scp=84976905636&partnerID=8YFLogxK
U2 - 10.1021/acs.jpcb.6b03983
DO - 10.1021/acs.jpcb.6b03983
M3 - Artículo
SN - 1520-6106
VL - 120
SP - 5655
EP - 5661
JO - Journal of Physical Chemistry B
JF - Journal of Physical Chemistry B
IS - 25
ER -