TY - JOUR
T1 - Encephalitis Associated with SARS-CoV-2 Infection in a Child with Chiari Malformation Type I
AU - Reyes-Ruiz, José Manuel
AU - Manrique-Calvillo, Claudia
AU - Martínez-Mier, Gustavo
AU - Servin-Monroy, Arturo Osvaldo
AU - Mota-García, Gilraed
AU - de Maria Lugo-Miranda, Flor
AU - Villegas-Del Angel, Enrique
AU - Zarate-Segura, Paola
AU - Bastida-Gonzalez, Fernando
AU - Del Angel, Rosa Maria
N1 - Publisher Copyright:
© 2023 International Institute of Anticancer Research. All rights reserved.
PY - 2023/3
Y1 - 2023/3
N2 - Background/Aim: There is increasing evidence that patients infected with SARS-CoV-2 develop neurological manifestations such as encephalitis. The purpose of this article was to present a case of viral encephalitis associated with SARS-CoV-2 in a 14-year-old child with Chiari malformation type I. Case Report: The patient manifested frontal headache, nausea, vomiting, skin pallor, right side Babinski sign and was diagnosed with Chiari malformation type I. He was admitted with generalized seizures and suspected encephalitis. Brain inflammation and viral RNA in the cerebrospinal fluid suggested SARS-CoV-2 encephalitis. These findings indicate that the SARS-CoV-2 test in CSF of patients with neurological manifestations, confusion, and fever during the COVID-19 pandemic should be carried out even when there is no evidence of respiratory infection. To our knowledge, this presentation of encephalitis associated with COVID-19 has not yet been reported in a patient with a congenital syndrome such as Chiari malformation type I. Conclusion: Further clinical data are needed to determine the complications of encephalitis due to SARS-CoV-2 in patients with Chiari malformation type I to standardize diagnosis and treatment.
AB - Background/Aim: There is increasing evidence that patients infected with SARS-CoV-2 develop neurological manifestations such as encephalitis. The purpose of this article was to present a case of viral encephalitis associated with SARS-CoV-2 in a 14-year-old child with Chiari malformation type I. Case Report: The patient manifested frontal headache, nausea, vomiting, skin pallor, right side Babinski sign and was diagnosed with Chiari malformation type I. He was admitted with generalized seizures and suspected encephalitis. Brain inflammation and viral RNA in the cerebrospinal fluid suggested SARS-CoV-2 encephalitis. These findings indicate that the SARS-CoV-2 test in CSF of patients with neurological manifestations, confusion, and fever during the COVID-19 pandemic should be carried out even when there is no evidence of respiratory infection. To our knowledge, this presentation of encephalitis associated with COVID-19 has not yet been reported in a patient with a congenital syndrome such as Chiari malformation type I. Conclusion: Further clinical data are needed to determine the complications of encephalitis due to SARS-CoV-2 in patients with Chiari malformation type I to standardize diagnosis and treatment.
KW - COVID-19
KW - Chiari malformation type I
KW - SARS-CoV-2
KW - encephalitis
UR - http://www.scopus.com/inward/record.url?scp=85149548612&partnerID=8YFLogxK
U2 - 10.21873/invivo.13165
DO - 10.21873/invivo.13165
M3 - Artículo
C2 - 36881093
AN - SCOPUS:85149548612
SN - 0258-851X
VL - 37
SP - 933
EP - 939
JO - In Vivo
JF - In Vivo
IS - 2
ER -